Ahmet Bugra Tufan
Overview
Explore the profile of Ahmet Bugra Tufan including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
53
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Recent Articles
1.
TSG101 associates with PARP1 and is essential for PARylation and DNA damage-induced NF-κB activation
Tufan A, Lazarow K, Kolesnichenko M, Sporbert A, von Kries J, Scheidereit C
EMBO J
. 2022 Sep;
41(21):e110372.
PMID: 36124865
In a genome-wide screening for components of the dsDNA-break-induced IKK-NF-κB pathway, we identified scores of regulators, including tumor susceptibility gene TSG101. TSG101 is essential for DNA damage-induced formation of cellular...
2.
Kolesnichenko M, Mikuda N, Hopken U, Kargel E, Uyar B, Tufan A, et al.
EMBO J
. 2021 Jan;
40(6):e104296.
PMID: 33459422
The IκB kinase (IKK)-NF-κB pathway is activated as part of the DNA damage response and controls both inflammation and resistance to apoptosis. How these distinct functions are achieved remained unknown....
3.
Mikuda N, Kolesnichenko M, Beaudette P, Popp O, Uyar B, Sun W, et al.
EMBO J
. 2018 Nov;
37(24).
PMID: 30467221
The IκB kinase (IKK) is considered to control gene expression primarily through activation of the transcription factor NF-κB. However, we show here that IKK additionally regulates gene expression on post-transcriptional...