Ahmed Z El-Hashim
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Explore the profile of Ahmed Z El-Hashim including associated specialties, affiliations and a list of published articles.
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26
Citations
273
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Recent Articles
1.
El-Hashim A, Khajah M, Orabi K, Balakrishnan S, Sary H, Barakat A
Pharm Biol
. 2024 Apr;
62(1):326-340.
PMID: 38584568
Context: Asthma presents a global health challenge. The main pharmacotherapy is synthetic chemicals and biological-based drugs that are costly, and have significant side effects. In contrast, use of natural products,...
2.
Ezeamuzie C, Rao M, El-Hashim A, Philip E, Phillips O
Int Immunopharmacol
. 2022 Jan;
105:108558.
PMID: 35091338
We have recently reported the discovery of a series of oxazolidinone hydroxamic acid derivatives that are potent inhibitors of 5-lipoxygenase (5-LO) [arachidonate 5-lipoxygenase; EC 1.13.11.34]. We now report that one...
3.
Al-Kandery A, Rao M, El-Hashim A
Respir Res
. 2021 Nov;
22(1):296.
PMID: 34794450
Background: Cough hypersensitivity is a major characteristic feature associated with several types of cough, including chronic cough, but its underlying mechanisms remain to be fully understood. Inflammatory mediators, such as...
4.
El-Hashim A, Khajah M, Orabi K, Balakrishnan S, Sary H, Abdelali A
Front Pharmacol
. 2020 Oct;
11:551683.
PMID: 33123005
The treatment of allergic diseases, such as asthma, with both conventional and novel therapies presents a challenge both in terms of optimal effect and cost. On the other hand, traditional...
5.
Safar H, El-Hashim A, Amoudy H, Mustafa A
Front Pharmacol
. 2020 Oct;
11:532199.
PMID: 33101014
Despite significant advances, asthma remains a cause of premature death, and current treatments are suboptimal. Antigen-specific Th2 cells and their cytokines are primary mediators of the pathophysiological changes seen in...
6.
Khajah M, El-Hashim A, Orabi K, Hawai S, Sary H
PLoS One
. 2020 Oct;
15(10):e0233938.
PMID: 33095803
Background: Onion is one of the most commonly used plants in the traditional medicine for the treatment of various diseases. We recently demonstrated the anti-inflammatory properties of onion bulb extract...
7.
El-Hashim A, Khajah M, Babyson R, Renno W, Ezeamuzie C, Benter I, et al.
PLoS One
. 2019 Nov;
14(11):e0224163.
PMID: 31675376
The angiotensin-(1-7) [Ang-(1-7)]/MAS1 receptor signaling axis is a key endogenous anti-inflammatory signaling pathway. However, the mechanisms by which its mediates the anti-inflammatory effects are not completely understood. Using an allergic...
8.
Al-Shamlan F, El-Hashim A
Respir Res
. 2019 Jun;
20(1):110.
PMID: 31170972
Background: Inhaled bradykinin (BK) has been reported to both sensitize and induce cough but whether BK can centrally sensitize the cough reflex is not fully established. In this study, using...
9.
Khajah M, Orabi K, Hawai S, Sary H, El-Hashim A
J Ethnopharmacol
. 2019 Jun;
241:112008.
PMID: 31158441
Ethnopharmacological Relevance: The use of nutraceutical-based products has increased in recent years due to their demonstrated efficacy and their good safety profile. Onion is one of the most commonly used...
10.
Akhtar S, Chandrasekhar B, Yousif M, Renno W, Benter I, El-Hashim A
Nanomedicine
. 2019 Mar;
18:78-89.
PMID: 30844576
We investigated whether chronic administration of nano-sized polyamidoamine (PAMAM) dendrimers can have beneficial effects on diabetes-induced vascular dysfunction by inhibiting the epidermal growth factor receptor (EGFR)-ERK1/2-Rho kinase (ROCK)-a pathway known...