Ahmed S Abouhashem
Overview
Explore the profile of Ahmed S Abouhashem including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
117
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Recent Articles
1.
Verma S, Sen C, Srivastava R, Gnyawali S, Katiyar P, Sahi A, et al.
Mol Ther
. 2025 Jan;
33(3):950-969.
PMID: 39863930
Diabetic wounds are complicated by underlying peripheral vasculopathy. Reliance on vascular endothelial growth factor (VEGF) therapy to improve perfusion makes logical sense, yet clinical study outcomes on rescuing diabetic wound...
2.
Srivastava R, Singh K, Abouhashem A, Kumar M, Kacar S, Verma S, et al.
iScience
. 2023 Aug;
26(9):107533.
PMID: 37636079
Fetal skin achieves scarless wound repair. Dermal fibroblasts play a central role in extracellular matrix deposition and scarring outcomes. Both fetal and gingival wound repair share minimal scarring outcomes. We...
3.
Abouhashem A, Singh K, Srivastava R, Liu S, Mathew-Steiner S, Gu X, et al.
bioRxiv
. 2023 Jun;
PMID: 37292819
Human death marks the end of organismal life under conditions such that the components of the human body continue to be alive. Such postmortem cellular survival depends on the nature...
4.
Gharbia F, Abouhashem A, Moqidem Y, Elbaz A, Abdellatif A, Singh K, et al.
Sci Rep
. 2023 Jan;
13(1):886.
PMID: 36650180
Wound healing is a well-organized dynamic process involving coordinated consecutive phases: homeostasis, inflammation, proliferation and resolution. Fibroblasts play major roles in skin wound healing such as in wound contraction and...
5.
Gordillo G, Guda P, Singh K, Biswas A, Abouhashem A, Rustagi Y, et al.
Mol Ther
. 2022 Nov;
31(5):1402-1417.
PMID: 36380587
Extracellular vesicles (EVs) are nanovesicles released by all eukaryotic cells. This work reports the first nanoscale fluorescent visualization of tumor-originating vesicles bearing an angiogenic microRNA (miR)-126 cargo. In a validated...
6.
Singh K, Rustagi Y, Abouhashem A, Tabasum S, Verma P, Hernandez E, et al.
J Clin Invest
. 2022 Jul;
132(17).
PMID: 35819852
An extreme chronic wound tissue microenvironment causes epigenetic gene silencing. An unbiased whole-genome methylome was studied in the wound-edge tissue of patients with chronic wounds. A total of 4,689 differentially...
7.
Wisler J, Singh K, McCarty A, Harkless R, Karpurapu M, Hernandez E, et al.
Shock
. 2022 Jun;
57(6):218-227.
PMID: 35759303
Introduction: Survivors of sepsis exhibit persistent immunosuppression. Epigenetic events may be responsible for some of these immunosuppressive changes. During sepsis circulating exosomes contain large quantities of DNA methyltransferase (DNMT) mRNAs....
8.
Rustagi Y, Abouhashem A, Verma P, Verma S, Hernandez E, Liu S, et al.
Diabetes
. 2022 Feb;
71(5):1149-1165.
PMID: 35192691
Therapeutic vascular endothelial growth factor (VEGF) replenishment has met with limited success for the management of critical limb-threatening ischemia. To improve outcomes of VEGF therapy, we applied single-cell RNA sequencing...
9.
Abouhashem A, Singh K, Azzazy H, Sen C
Antioxid Redox Signal
. 2020 Apr;
33(2):59-65.
PMID: 32323565
Human lungs single-cell RNA sequencing data from healthy donors (elderly and young; GEO accession no. GSE122960) were analyzed to isolate and specifically study gene expression in alveolar type II cells....