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Ahmed Abu-Fayyad

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Articles 8
Citations 45
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Recent Articles
1.
Salawi A, Sonju J, Kamal M, Abu-Fayyad A, Al Hagbani T, Nazzal S
Drug Dev Ind Pharm . 2021 Oct; 47(8):1335-1341. PMID: 34622736
Objective: The goals of this study were to (1) delineate a technique to prepare stable aqueous vitamin E/Soluplus dispersions; (2) characterize films cast from the aqueous dispersions; and (3) demonstrate...
2.
Abu-Fayyad A, Nazzal S
J Am Oil Chem Soc . 2021 Feb; 94(9):1209-1217. PMID: 33518766
Vitamin E refers to a family of eight tocopherols (T) and tocotrienol (T3) isomers. Due to the unique pharmacological and anticancer activity of the individual isomers, there is a need...
3.
Abu-Fayyad A, Kamal M, Carroll J, Dragoi A, Cody R, Cardelli J, et al.
Int J Pharm . 2017 Dec; 536(1):146-157. PMID: 29195915
Vitamin E TPGS is a tocopherol (α-T) based nonionic surfactant that was used in the formulation of the Tocosol™ paclitaxel nanoemulsion, which was withdrawn from phase III clinical trials. Unlike...
4.
Abu-Fayyad A, Nazzal S
Int J Pharm . 2017 Jun; 528(1-2):463-470. PMID: 28627455
Gemcitabine is the first line therapy for pancreatic cancer. It is, however, extensively metabolized to the inactive form by deamination enzymatic reaction. Conjugation of gemcitabine with fatty acids on its...
5.
Abu-Fayyad A, Nazzal S
Int J Pharm . 2017 Jun; 529(1-2):75-86. PMID: 28627454
The anticancer activity of water soluble methoxy polyethylene glycol (mPEG) derivatives of tocotrienol (T3) isomers of vitamin E was previously found to be reduced when compared to the parent free...
6.
Abu-Fayyad A, Nazzal S
Int J Pharm . 2017 Jan; 519(1-2):145-156. PMID: 28093324
Vitamin E refers to a group of saturated tocopherol (T) isomers and the biologically more active unsaturated tocotrienol (T) isomers. PEGylated α-tocopherol, commercially known as Vitamin E TPGS, has been...
7.
Abu-Fayyad A, Behery F, Sallam A, Alqahtani S, Ebrahim H, El Sayed K, et al.
Eur J Pharm Biopharm . 2015 Aug; 96:185-95. PMID: 26235392
Vitamin E refers to a family of eight isomers divided into two subgroups, tocopherols and the therapeutically active tocotrienols (T3). The PEGylated α-tocopherol isomer of vitamin E (vitamin E TPGS)...
8.
Alayoubi A, Abu-Fayyad A, Rawas-Qalaji M, Sylvester P, Nazzal S
Pharm Dev Technol . 2014 Mar; 20(5):555-61. PMID: 24621375
Recently there has been a growing interest in vitamin E for its potential use in cancer therapy. The objective of this work was therefore to formulate a physically stable parenteral...