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Ahmad Anjak

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Articles 7
Citations 102
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Recent Articles
1.
Ren X, Roessler A, Lynch 4th T, Haar L, Mallick F, Lui Y, et al.
Am J Physiol Heart Circ Physiol . 2018 Dec; 316(3):H543-H553. PMID: 30575436
Timely reperfusion is still the most effective approach to limit infarct size in humans. Yet, despite advances in care and reduction in door-to-balloon times, nearly 25% of patients develop heart...
2.
Pritchard T, Kawase Y, Haghighi K, Anjak A, Cai W, Jiang M, et al.
PLoS One . 2013 Dec; 8(12):e80717. PMID: 24312496
Impaired sarcoplasmic reticulum calcium cycling and depressed contractility are key characteristics in heart failure. Defects in sarcoplasmic reticulum function are characterized by decreased SERCA2a Ca-transport that is partially attributable to...
3.
Basford J, Koch S, Anjak A, Singh V, Krause E, Robbins N, et al.
PLoS One . 2013 Dec; 8(11):e82026. PMID: 24312398
Valvular disease is common in patients with Marfan syndrome and can lead to cardiomyopathy. However, some patients develop cardiomyopathy in the absence of hemodynamically significant valve dysfunction, suggesting alternative mechanisms...
4.
Anjak A, Lopez-Candales A, Lopez F, Harris D, Elwing J
Echocardiography . 2013 Oct; 31(4):508-15. PMID: 24134496
Background: A growing body of evidence seems to suggest that reduction in right ventricular (RV) systolic function is not only associated with both development of symptoms associated with pulmonary arterial...
5.
Koch S, Haworth K, Robbins N, Smith M, Lather N, Anjak A, et al.
Ultrasound Med Biol . 2013 Jun; 39(11):2034-43. PMID: 23791351
Detailed studies in animal models to assess the importance of aging animals in cardiovascular research are rather scarce. The increase in mouse models used to study cardiovascular disease makes the...
6.
Florea S, Anjak A, Cai W, Qian J, Vafiadaki E, Figueria S, et al.
Basic Res Cardiol . 2012 Jul; 107(5):279. PMID: 22777184
The activity of protein phosphatase-1 (PP1) inhibitor-1 (I-1) is antithetically modulated by the cAMP-protein kinase A (PKA) and Ca(2+)-protein kinase C (PKC) signaling axes. β-adrenergic (β-AR) stimulation results in PKA-phosphorylation...
7.
Haghighi K, Pritchard T, Bossuyt J, Waggoner J, Yuan Q, Fan G, et al.
J Mol Cell Cardiol . 2011 Dec; 52(3):773-82. PMID: 22155237
Depressed Ca-handling in cardiomyocytes is frequently attributed to impaired sarcoplasmic reticulum (SR) function in human and experimental heart failure. Phospholamban (PLN) is a key regulator of SR and cardiac function,...