Agusti Brugues
Overview
Explore the profile of Agusti Brugues including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
837
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0
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Recent Articles
1.
Chen T, Callan-Jones A, Fedorov E, Ravasio A, Brugues A, Ong H, et al.
Nat Phys
. 2019 Apr;
15:393-402.
PMID: 30984281
Cell migration over heterogeneous substrates during wound healing or morphogenetic processes leads to shape changes driven by different organizations of the actin cytoskeleton and by functional changes including lamellipodial protrusions...
2.
Rodriguez-Franco P, Brugues A, Marin-Llaurado A, Conte V, Solanas G, Batlle E, et al.
Nat Mater
. 2017 Sep;
16(10):1029-1037.
PMID: 28892054
For an organism to develop and maintain homeostasis, cell types with distinct functions must often be separated by physical boundaries. The formation and maintenance of such boundaries are commonly attributed...
3.
Labernadie A, Kato T, Brugues A, Serra-Picamal X, Derzsi S, Arwert E, et al.
Nat Cell Biol
. 2017 Feb;
19(3):224-237.
PMID: 28218910
Cancer-associated fibroblasts (CAFs) promote tumour invasion and metastasis. We show that CAFs exert a physical force on cancer cells that enables their collective invasion. Force transmission is mediated by a...
4.
Brugues A, Anon E, Conte V, Veldhuis J, Gupta M, Colombelli J, et al.
Nat Phys
. 2016 Jun;
10(9):683-690.
PMID: 27340423
A fundamental feature of multicellular organisms is their ability to self-repair wounds through the movement of epithelial cells into the damaged area. This collective cellular movement is commonly attributed to...
5.
Plutoni C, Bazellieres E, Le Borgne-Rochet M, Comunale F, Brugues A, Seveno M, et al.
J Cell Biol
. 2016 Jan;
212(2):199-217.
PMID: 26783302
Collective cell migration (CCM) is essential for organism development, wound healing, and metastatic transition, the primary cause of cancer-related death, and it involves cell-cell adhesion molecules of the cadherin family....
6.
Perrault C, Brugues A, Bazellieres E, Ricco P, Lacroix D, Trepat X
Biophys J
. 2015 Oct;
109(8):1533-6.
PMID: 26488643
Endothelial cells are constantly exposed to fluid shear stresses that regulate vascular morphogenesis, homeostasis, and disease. The mechanical responses of endothelial cells to relatively high shear flow such as that...
7.
Ravasio A, Cheddadi I, Chen T, Pereira T, Ong H, Bertocchi C, et al.
Nat Commun
. 2015 Jul;
6:7683.
PMID: 26158873
Closure of wounds and gaps in tissues is fundamental for the correct development and physiology of multicellular organisms and, when misregulated, may lead to inflammation and tumorigenesis. To re-establish tissue...
8.
Vedula S, Peyret G, Cheddadi I, Chen T, Brugues A, Hirata H, et al.
Nat Commun
. 2015 Jan;
6:6111.
PMID: 25608921
The closure of gaps within epithelia is crucial to maintain its integrity during biological processes such as wound healing and gastrulation. Depending on the distribution of extracellular matrix, gap closure...
9.
Vedula S, Hirata H, Nai M, Brugues A, Toyama Y, Trepat X, et al.
Nat Mater
. 2013 Dec;
13(1):87-96.
PMID: 24292420
The ability of skin to act as a barrier is primarily determined by the efficiency of skin cells to maintain and restore its continuity and integrity. In fact, during wound...