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Agnieszka Nikiforuk

Explore the profile of Agnieszka Nikiforuk including associated specialties, affiliations and a list of published articles. Areas
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Articles 87
Citations 1050
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Recent Articles
1.
Partyka A, Golebiowska J, Marciniec K, Canale V, Trybala W, Satala G, et al.
Pharmacol Rep . 2025 Mar; PMID: 40064751
Background: Novel antipsychotics are characterized by multitarget profile of action, affecting among others, dopamine and serotonin receptors. In a series of experiments, we designed, synthesized and examined two new isoquinoline-sulfonamide...
2.
Zajdel P, Matloka M, Konieczny J, Kos T, Lammers J, Cavalco N, et al.
J Pharmacol Exp Ther . 2025 Mar; 392(2):100055. PMID: 40023605
Parkinson's disease (PD) treatment focuses mainly on the augmentation of dopamine transmission, but to alleviate adverse motor effects accompanying L-DOPA use, additional treatments with serotonergic (5-HT) medications may be considered....
3.
Popik P, Cyrano E, Golebiowska J, Malikowska-Racia N, Potasiewicz A, Nikiforuk A
PLoS One . 2024 Nov; 19(11):e0307794. PMID: 39514582
The rapid decrease of light intensity is a potent stimulus of rats' activity. The nature of this activity, including the character of social behavior and the composition of concomitant ultrasonic...
4.
Kolasa M, Nikiforuk A, Korlatowicz A, Solich J, Potasiewicz A, Dziedzicka-Wasylewska M, et al.
Psychopharmacology (Berl) . 2024 Jul; PMID: 39030424
No abstract available.
5.
Kolasa M, Nikiforuk A, Korlatowicz A, Solich J, Potasiewicz A, Dziedzicka-Wasylewska M, et al.
Psychopharmacology (Berl) . 2024 Jul; PMID: 38963553
Rationale: Our study aimed to unravel the unknown mechanisms behind the exceptional efficacy of Psilocybin (PSI) in treating treatment-resistant depression (TRD). Focusing on Wistar-Kyoto (WKY) rats with a TRD phenotype...
6.
Popik P, Cyrano E, Piotrowska D, Holuj M, Golebiowska J, Malikowska-Racia N, et al.
Front Pharmacol . 2024 Jan; 14:1329424. PMID: 38269275
Traditional methods of rat social behavior assessment are extremely time-consuming and susceptible to the subjective biases. In contrast, novel digital techniques allow for rapid and objective measurements. This study sought...
7.
Piotrowska D, Potasiewicz A, Popik P, Nikiforuk A
Eur Neuropsychopharmacol . 2023 Oct; 78:30-42. PMID: 37866191
Social and cognitive dysfunctions are the most persistent symptoms of schizophrenia. Since oxytocin (OXT) is known to play a role in social functions and modulates cognitive processes, we investigated the...
8.
Galezowski M, Fabritius C, Pesonen U, Salo H, Olszak-Plachta M, Czerwinska K, et al.
Bioorg Med Chem Lett . 2023 Oct; 96:129497. PMID: 37806499
In this study, we present the discovery and pharmacological characterization of a new series of 6-piperazinyl-7-azaindoles. These compounds demonstrate potent antagonism and selectivity against the 5-HT receptor. Our research primarily...
9.
Grychowska K, Pietrus W, Kulawik L, Bento O, Satala G, Bantreil X, et al.
Molecules . 2023 Feb; 28(3). PMID: 36770761
Salt bridge (SB, double-charge-assisted hydrogen bonds) formation is one of the strongest molecular non-covalent interactions in biological systems, including ligand-receptor complexes. In the case of G-protein-coupled receptors, such an interaction...
10.
Gzielo K, Piotrowska D, Litwa E, Popik P, Nikiforuk A
Sci Rep . 2023 Feb; 13(1):1918. PMID: 36732579
A wide body of evidence suggests a relationship between maternal immune activation (MIA) and neurodevelopmental disorders such as autism spectrum disorder (ASD). Since social and communicative deficits are included in...