Piotr Popik
Overview
Explore the profile of Piotr Popik including associated specialties, affiliations and a list of published articles.
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Articles
123
Citations
1827
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Recent Articles
1.
Partyka A, Golebiowska J, Marciniec K, Canale V, Trybala W, Satala G, et al.
Pharmacol Rep
. 2025 Mar;
PMID: 40064751
Background: Novel antipsychotics are characterized by multitarget profile of action, affecting among others, dopamine and serotonin receptors. In a series of experiments, we designed, synthesized and examined two new isoquinoline-sulfonamide...
2.
Zajdel P, Matloka M, Konieczny J, Kos T, Lammers J, Cavalco N, et al.
J Pharmacol Exp Ther
. 2025 Mar;
392(2):100055.
PMID: 40023605
Parkinson's disease (PD) treatment focuses mainly on the augmentation of dopamine transmission, but to alleviate adverse motor effects accompanying L-DOPA use, additional treatments with serotonergic (5-HT) medications may be considered....
3.
Cyrano E, Popik P
Pharmacol Rep
. 2024 Nov;
77(1):135-144.
PMID: 39602080
Background: Serotonergic psychedelics, which display a high affinity and specificity for 5-HT receptors like 2,5-dimethoxy-4-iodoamphetamine (DOI), reliably induce a head-twitch response in rodents characterized by paroxysmal, high-frequency head rotations. Traditionally,...
4.
Popik P, Cyrano E, Golebiowska J, Malikowska-Racia N, Potasiewicz A, Nikiforuk A
PLoS One
. 2024 Nov;
19(11):e0307794.
PMID: 39514582
The rapid decrease of light intensity is a potent stimulus of rats' activity. The nature of this activity, including the character of social behavior and the composition of concomitant ultrasonic...
5.
Popik P, Cyrano E, Piotrowska D, Holuj M, Golebiowska J, Malikowska-Racia N, et al.
Front Pharmacol
. 2024 Jan;
14:1329424.
PMID: 38269275
Traditional methods of rat social behavior assessment are extremely time-consuming and susceptible to the subjective biases. In contrast, novel digital techniques allow for rapid and objective measurements. This study sought...
6.
Piotrowska D, Potasiewicz A, Popik P, Nikiforuk A
Eur Neuropsychopharmacol
. 2023 Oct;
78:30-42.
PMID: 37866191
Social and cognitive dysfunctions are the most persistent symptoms of schizophrenia. Since oxytocin (OXT) is known to play a role in social functions and modulates cognitive processes, we investigated the...
7.
Malikowska-Racia N, Koniewski M, Golebiowska J, Popik P
J Psychopharmacol
. 2023 Oct;
37(11):1149-1156.
PMID: 37842884
Background: In clinical studies, psychedelics including psilocybin and D-lysergic acid diethylamide (LSD) demonstrate rapid and persistent antidepressant effects. Since the effective treatment with psychedelics is usually provided with psychotherapy, it...
8.
Grychowska K, Lopez-Sanchez U, Vitalis M, Canet G, Satala G, Olejarz-Maciej A, et al.
J Med Chem
. 2023 Oct;
66(21):14928-14947.
PMID: 37797083
The multifactorial origin and neurochemistry of Alzheimer's disease (AD) call for the development of multitarget treatment strategies. We report a first-in-class triple acting compound that targets serotonin type 6 and...
9.
Szczepanska K, Bojarski A, Popik P, Malikowska-Racia N
Pharmacol Rep
. 2023 Aug;
75(5):1291-1298.
PMID: 37572216
Background: Although the terms "agonist" and "antagonist" have been used to classify sigma-1 receptor (σR) ligands, an unambiguous definition of the functional activity is often hard. In order to determine...
10.
Gzielo K, Piotrowska D, Litwa E, Popik P, Nikiforuk A
Sci Rep
. 2023 Feb;
13(1):1918.
PMID: 36732579
A wide body of evidence suggests a relationship between maternal immune activation (MIA) and neurodevelopmental disorders such as autism spectrum disorder (ASD). Since social and communicative deficits are included in...