Afam A Okoye
Overview
Explore the profile of Afam A Okoye including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
935
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Haeseleer F, Eichholz K, Tareen S, Iwamoto N, Roederer M, Kirchhoff F, et al.
AIDS Res Hum Retroviruses
. 2020 Sep;
36(12):998-1009.
PMID: 32988211
The success of chimeric antigen receptor (CAR) T cell therapies for treating leukemia has resulted in a booming interest for the technology. Expression of a CAR in T cells allows...
12.
Okoye A, DeGottardi M, Fukazawa Y, Vaidya M, Abana C, Konfe A, et al.
J Immunol
. 2019 Oct;
203(11):2928-2943.
PMID: 31653683
Although IL-15 has been implicated in the pathogenic hyperimmune activation that drives progressive HIV and SIV infection, as well as in the generation of HIV/SIV target cells, it also supports...
13.
Khanal S, Fennessey C, OBrien S, Thorpe A, Reid C, Immonen T, et al.
J Virol
. 2019 Oct;
94(1).
PMID: 31597757
Genetically barcoded viral populations are powerful tools for evaluating the overall viral population structure as well as assessing the dynamics and evolution of individual lineages over time. Barcoded viruses are...
14.
Bender A, Simonetti F, Kumar M, Fray E, Bruner K, Timmons A, et al.
Cell Host Microbe
. 2019 Jul;
26(1):73-85.e4.
PMID: 31295427
Evaluation of HIV cure strategies is complicated by defective proviruses that persist in ART-treated patients but are irrelevant to cure. Non-human primates (NHP) are essential for testing cure strategies. However,...
15.
Okoye A, Hansen S, Vaidya M, Fukazawa Y, Park H, Duell D, et al.
Nat Med
. 2018 Aug;
24(9):1430-1440.
PMID: 30082858
Prophylactic vaccination of rhesus macaques with rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens (RhCMV/SIV) elicits immune responses that stringently control highly pathogenic SIV infection, with subsequent apparent...
16.
Chomont N, Okoye A, Favre D, Trautmann L
AIDS
. 2017 Nov;
32(3):293-298.
PMID: 29135580
No abstract available.
17.
DeGottardi M, Okoye A, Vaidya M, Talla A, Konfe A, Reyes M, et al.
J Immunol
. 2016 Jul;
197(4):1183-98.
PMID: 27430715
IL-15 has been implicated as a key regulator of T and NK cell homeostasis in multiple systems; however, its specific role in maintaining peripheral T and NK cell populations relative...
18.
Okoye A, Rohankhedkar M, Konfe A, Abana C, Reyes M, Clock J, et al.
J Immunol
. 2015 Sep;
195(9):4292-305.
PMID: 26416281
Aging is associated with gradual deterioration of adaptive immune function, a hallmark of which is the profound loss of naive T cells (TN) associated with decline in thymic output and...
19.
Fukazawa Y, Lum R, Okoye A, Park H, Matsuda K, Bae J, et al.
Nat Med
. 2015 Jan;
21(2):132-9.
PMID: 25599132
Chronic-phase HIV and simian immunodeficiency virus (SIV) replication is reduced by as much as 10,000-fold in elite controllers (ECs) compared with typical progressors (TPs), but sufficient viral replication persists in...
20.
Okoye A, Picker L
Immunol Rev
. 2013 Jun;
254(1):54-64.
PMID: 23772614
The hallmark of acquired immunodeficiency syndrome (AIDS) pathogenesis is a progressive depletion of CD4(+) T-cell populations in close association with progressive impairment of cellular immunity and increasing susceptibility to opportunistic...