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Adrian T Ting

Explore the profile of Adrian T Ting including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 1705
Followers 0
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Recent Articles
1.
Wu Z, Xiao H, Kloeber J, Ouyang Y, Yin P, Huang J, et al.
Cancer Commun (Lond) . 2025 Jan; PMID: 39754711
No abstract available.
2.
Sun N, Carr A, Krogman E, Chawla Y, Zhong J, Guttormson M, et al.
bioRxiv . 2024 Aug; PMID: 39149268
Cytotoxic T cells produce interferon gamma (IFNγ), which plays a critical role in anti-microbial and anti-tumor responses. However, it is not clear whether T cell-derived IFNγ directly kills infected and...
3.
Chen L, He Z, Reis B, Gelles J, Chipuk J, Ting A, et al.
Cell Mol Immunol . 2022 Apr; 19(7):777-790. PMID: 35468944
The food colorant Red 40 is an environmental risk factor for colitis development in mice with increased expression of interleukin (IL)-23. This immune response is mediated by CD4 T cells,...
4.
Ang R, Chan M, Legarda D, Sundberg J, Sun S, Gillespie V, et al.
Proc Natl Acad Sci U S A . 2021 Dec; 118(50). PMID: 34887354
SHARPIN, together with RNF31/HOIP and RBCK1/HOIL1, form the linear ubiquitin chain assembly complex (LUBAC) E3 ligase that catalyzes M1-linked polyubiquitination. Mutations in and in humans and in mice lead to...
5.
Chun N, Ang R, Chan M, Fairchild R, Baldwin 3rd W, Horwitz J, et al.
JCI Insight . 2021 Nov; 6(24). PMID: 34752416
TNF ligation of TNF receptor 1 (TNFR1) promotes either inflammation and cell survival by (a) inhibiting RIPK1's death-signaling function and activating NF-κB or (b) causing RIPK1 to associate with the...
6.
Taft J, Markson M, Legarda D, Patel R, Chan M, Malle L, et al.
Cell . 2021 Aug; 184(17):4447-4463.e20. PMID: 34363755
TANK binding kinase 1 (TBK1) regulates IFN-I, NF-κB, and TNF-induced RIPK1-dependent cell death (RCD). In mice, biallelic loss of TBK1 is embryonically lethal. We discovered four humans, ages 32, 26,...
7.
Xu X, Kalac M, Markson M, Chan M, Brody J, Bhagat G, et al.
Cell Death Dis . 2020 Feb; 11(2):94. PMID: 32024820
Adult T-cell leukemia/lymphoma (ATLL) is a malignancy of mature T cells associated with chronic infection by human T-cell lymphotropic virus type-1 (HTLV-1). ATLL patients with aggressive subtypes have dismal outcomes....
8.
Priem D, Devos M, Druw S, Martens A, Slowicka K, Ting A, et al.
Cell Death Dis . 2020 Jan; 11(1):60. PMID: 31974345
The original version of this article contained an error in the name of one of the co-authors (Wim Declercq). This has been corrected in the PDF and HTML versions.
9.
Garcia-Carmona Y, Ting A, Radigan L, Athuluri Divakar S, Chavez J, Meffre E, et al.
Front Immunol . 2019 Dec; 10:2772. PMID: 31839795
[This corrects the article DOI: 10.3389/fimmu.2018.02125.].
10.
Gelles J, Mohammed J, Santos L, Legarda D, Ting A, Chipuk J
Dev Cell . 2019 Oct; 51(2):277-291.e4. PMID: 31564612
Quantifying cytostatic and cytotoxic outcomes are integral components of characterizing perturbagens used as research tools and in drug discovery pipelines. Furthermore, data-rich acquisition, coupled with robust methods for analysis, is...