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Adrian Santos-Ledo

Explore the profile of Adrian Santos-Ledo including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 104
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Recent Articles
1.
Perez-Montes C, Hernandez-Garcia R, Jimenez-Cubides J, DeOliveira-Mello L, Velasco A, Arevalo R, et al.
Neural Regen Res . 2025 Jan; PMID: 39878527
The visual system of teleost fish grows continuously, which is a useful model for studying regeneration of the central nervous system. Glial cells are key for this process, but their...
2.
Santos-Ledo A, Garcia-Macia M
Antioxidants (Basel) . 2024 Mar; 13(3). PMID: 38539893
Melatonin is an indoleamine that has captured our attention since 1958 [...].
3.
Garcia-Macia M, Sierra V, Santos-Ledo A, de Luxan-Delgado B, Potes-Ochoa Y, Rodriguez-Gonzalez S, et al.
Foods . 2024 Feb; 13(3). PMID: 38338578
For fresh meat consumers, eating satisfaction is of utmost importance and tenderness is one of the most important characteristics in this regard. Our study examined beef of different animal biotypes...
4.
Perez-Montes C, Jimenez-Cubides J, Velasco A, Arevalo R, Santos-Ledo A, Garcia-Macia M
Antioxidants (Basel) . 2023 Dec; 12(12). PMID: 38136146
Zebrafish () present continuous growth and regenerate many parts of their body after an injury. Fish oligodendrocytes, microglia and astrocytes support the formation of new connections producing effective regeneration of...
5.
Derrick C, Szenker-Ravi E, Santos-Ledo A, Alqahtani A, Yusof A, Eley L, et al.
Hum Mol Genet . 2023 Oct; 33(2):150-169. PMID: 37815931
Developmental studies have shown that the evolutionarily conserved Wnt Planar Cell Polarity (PCP) pathway is essential for the development of a diverse range of tissues and organs including the brain,...
6.
Santos-Ledo A, Perez-Montes C, DeOliveira-Mello L, Arevalo R, Velasco A
J Comp Neurol . 2022 Dec; 531(4):515-527. PMID: 36477827
Oligodendrocytes are the myelinating cells in the central nervous system. In birds and mammals, the oligodendrocyte progenitor cells (OPCs) originate in the preoptic area (POA) of the hypothalamus. However, it...
7.
Derrick C, Santos-Ledo A, Eley L, Paramita I, Henderson D, Chaudhry B
Development . 2022 Mar; 149(9). PMID: 35352808
The establishment of the left-right axis is crucial for the placement, morphogenesis and function of internal organs. Left-right specification is proposed to be dependent on cilia-driven fluid flow in the...
8.
DeOliveira-Mello L, Vicente I, Gonzalez-Nunez V, Santos-Ledo A, Velasco A, Arevalo R, et al.
Biology (Basel) . 2022 Feb; 11(2). PMID: 35205114
Doublecortin (DCX) is a microtubule associated protein, essential for correct central nervous system development and lamination in the mammalian cortex. It has been demonstrated to be expressed in developing-but not...
9.
Murphy L, Santos-Ledo A, Dhanaseelan T, Eley L, Burns D, Henderson D, et al.
Dis Model Mech . 2021 Jul; 14(7). PMID: 34296752
Exercise may ameliorate the eventual heart failure inherent in human aging. In this study, we use zebrafish to understand how aging and exercise affect cardiomyocyte turnover and myocardial remodelling. We...
10.
Garcia-Macia M, Santos-Ledo A, Leslie J, Paish H, Collins A, Scott R, et al.
Hepatology . 2021 Jul; 74(6):3441-3459. PMID: 34233024
Background And Aims: NAFLD is the most common hepatic pathology in western countries and no treatment is currently available. NAFLD is characterized by the aberrant hepatocellular accumulation of fatty acids...