Adrian Macho-Gonzalez
Overview
Explore the profile of Adrian Macho-Gonzalez including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
148
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Recent Articles
1.
Khawaja R, Martin-Segura A, Santiago-Fernandez O, Sereda R, Lindenau K, McCabe M, et al.
Nat Aging
. 2025 Feb;
PMID: 39910244
Aging leads to progressive decline in organ and tissue integrity and function, partly due to loss of proteostasis and autophagy malfunctioning. A decrease with age in chaperone-mediated autophagy (CMA), a...
2.
Hernandez-Martin M, Garcimartin A, Bocanegra A, Macho-Gonzalez A, Garcia-Fernandez R, de Pascual-Teresa S, et al.
Int J Mol Sci
. 2024 Nov;
25(21).
PMID: 39518958
Silicon as a functional ingredient of restructured meat (RM) shows antidiabetic and hypocholesterolemic effects in a type 2 diabetes mellitus (T2DM) rat model. The present paper investigated the mechanisms involved...
3.
Hernandez-Martin M, Garcimartin A, Bocanegra A, Redondo-Castillejo R, Quevedo-Torremocha C, Macho-Gonzalez A, et al.
Foods
. 2024 Jun;
13(12).
PMID: 38928736
Silicon included in a restructured meat (RM) matrix (Si-RM) as a functional ingredient has been demonstrated to be a potential bioactive antidiabetic compound. However, the jejunal and hepatic molecular mechanisms...
4.
Jafari M, Macho-Gonzalez A, Diaz A, Lindenau K, Santiago-Fernandez O, Zeng M, et al.
Proc Natl Acad Sci U S A
. 2024 Jun;
121(26):e2317945121.
PMID: 38889154
Chaperone-mediated autophagy (CMA) is part of the mammalian cellular proteostasis network that ensures protein quality control, maintenance of proteome homeostasis, and proteome changes required for the adaptation to stress. Loss...
5.
Macho-Gonzalez A, Apaza Ticona L, Redondo-Castillejo R, Hernandez-Martin M, Sanchez-Muniz F, Hernaiz M, et al.
Food Chem
. 2024 Apr;
450:139339.
PMID: 38657343
Oxidative stress is prevalent in Type 2 Diabetes Mellitus (T2DM) and has been associated with high meat consumption. Carob Fruit Extract (CFE) contains phenolic compounds, making it a suitable functional...
6.
Hernandez-Martin M, Bocanegra A, Garcimartin A, Issa J, Redondo-Castillejo R, Macho-Gonzalez A, et al.
Methods Cell Biol
. 2024 Mar;
185:165-195.
PMID: 38556447
The mucosal surface of gastrointestinal tract is lined with epithelial cells that establish an effective barrier between the lumen and internal environment through intercellular junctions, preventing the passage of potentially...
7.
Cofrades S, Gomez-Estaca J, Alvarez M, Garcimartin A, Macho-Gonzalez A, Benedi J, et al.
Gels
. 2024 Jan;
10(1).
PMID: 38247756
Oleogels (OG) and gelled emulsions (GE) were elaborated with a mixture of olive and chia oils (80:20 ratio) without and with the incorporation of the health-related compound curcumin. These were...
8.
Hernandez-Martin M, Macho-Gonzalez A, Garcimartin A, Lopez-Oliva M, Bocanegra A, Redondo-Castillejo R, et al.
Food Funct
. 2024 Jan;
15(3):1513-1526.
PMID: 38229530
The impact of silicon as a functional ingredient in restructured meat (RM) on lipoprotein composition, metabolism, and oxidation on type 2 diabetes mellitus (T2DM) markers has never been studied. This...
9.
Redondo-Castillejo R, Garcimartin A, Hernandez-Martin M, Lopez-Oliva M, Bocanegra A, Macho-Gonzalez A, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982444
The metabolic syndrome (MS) is a cluster of risk factors, such as central obesity, hyperglycemia, dyslipidemia, and arterial hypertension, which increase the probability of causing premature mortality. The consumption of...
10.
Kaushik S, Juste Y, Lindenau K, Dong S, Macho-Gonzalez A, Santiago-Fernandez O, et al.
Sci Adv
. 2022 Nov;
8(46):eabq2733.
PMID: 36383673
Adipogenesis is a tightly orchestrated multistep process wherein preadipocytes differentiate into adipocytes. The most studied aspect of adipogenesis is its transcriptional regulation through timely expression and silencing of a vast...