Adrian E Granada
Overview
Explore the profile of Adrian E Granada including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
304
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ector C, Didier J, De Landtsheer S, Nordentoft M, Schmal C, Keilholz U, et al.
Mol Syst Biol
. 2025 Feb;
PMID: 39994450
The circadian clock regulates key physiological processes, including cellular responses to DNA damage. Circadian-based therapeutic strategies optimize treatment timing to enhance drug efficacy and minimize side effects, offering potential for...
2.
Ector C, Schmal C, Didier J, De Landtsheer S, Finger A, Muller-Marquardt F, et al.
Nat Commun
. 2024 Aug;
15(1):7205.
PMID: 39169017
The circadian clock, a fundamental biological regulator, governs essential cellular processes in health and disease. Circadian-based therapeutic strategies are increasingly gaining recognition as promising avenues. Aligning drug administration with the...
3.
Gutu N, Binish N, Keilholz U, Herzel H, Granada A
Commun Biol
. 2023 Nov;
6(1):1196.
PMID: 38001355
Cells must accurately and quickly detect DNA damage through a set of checkpoint mechanisms that enable repair and control proliferation. Heterogeneous levels of cellular stress and noisy signaling processes can...
4.
Schmal C, Monke G, Granada A
Methods Mol Biol
. 2022 May;
2482:35-54.
PMID: 35610418
Experiments that compare rhythmic properties across different genetic alterations and entrainment conditions underlie some of the most important breakthroughs in circadian biology. A robust estimation of the rhythmic properties of...
5.
Finger A, Jaschke S, Del Olmo M, Hurwitz R, Granada A, Herzel H, et al.
Sci Adv
. 2021 Jul;
7(30).
PMID: 34301601
Coupling between cell-autonomous circadian oscillators is crucial to prevent desynchronization of cellular networks and disruption of circadian tissue functions. While neuronal oscillators within the mammalian central clock, the suprachiasmatic nucleus,...
6.
Gabriel C, Del Olmo M, Zehtabian A, Jager M, Reischl S, van Dijk H, et al.
Nat Commun
. 2021 Jun;
12(1):3796.
PMID: 34145278
The cell biology of circadian clocks is still in its infancy. Here, we describe an efficient strategy for generating knock-in reporter cell lines using CRISPR technology that is particularly useful...
7.
Granada A, Jimenez A, Stewart-Ornstein J, Bluthgen N, Reber S, Jambhekar A, et al.
Mol Biol Cell
. 2020 Feb;
31(8):845-857.
PMID: 32049575
DNA-damaging chemotherapeutics are widely used in cancer treatments, but for solid tumors they often leave a residual tumor-cell population. Here we investigated how cellular states might affect the response of...
8.
Granada A, Bordyugov G, Kramer A, Herzel H
PLoS One
. 2013 Apr;
8(3):e59464.
PMID: 23544070
The endogenous circadian timing system has evolved to synchronize an organism to periodically recurring environmental conditions. Those external time cues are called Zeitgebers. When entrained by a Zeitgeber, the intrinsic...
9.
Granada A, Cambras T, Diez-Noguera A, Herzel H
Interface Focus
. 2012 Mar;
1(1):153-66.
PMID: 22419981
The suprachiasmatic nucleus (SCN) coordinates via multiple outputs physiological and behavioural circadian rhythms. The SCN is composed of a heterogeneous network of coupled oscillators that entrain to the daily light-dark...
10.
Abraham U, Granada A, Westermark P, Heine M, Kramer A, Herzel H
Mol Syst Biol
. 2010 Dec;
6:438.
PMID: 21119632
Circadian clocks are endogenous oscillators driving daily rhythms in physiology and behavior. Synchronization of these timers to environmental light-dark cycles ('entrainment') is crucial for an organism's fitness. Little is known...