Adrian B McDermott
Overview
Explore the profile of Adrian B McDermott including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
170
Citations
9405
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Spangler A, Shimberg G, Mantus G, Malek R, Cominsky L, Tsybovsky Y, et al.
Immunity
. 2025 Mar;
58(3):728-744.e9.
PMID: 40023164
Pre-existing immunity impacts vaccine responses to influenza, but directly connecting influenza infections early in life with immune responses decades later is difficult. However, H2N2 stopped circulating in the human population...
2.
Happe M, Lynch R, Fichtenbaum C, Heath S, Koletar S, Landovitz R, et al.
JCI Insight
. 2025 Feb;
10(4).
PMID: 39989458
BACKGROUNDHIV-1-specific broadly neutralizing monoclonal antibodies (bNAbs) have emerged as promising interventions with the potential to effectively treat and prevent HIV-1 infections. We conducted a phase I clinical trial evaluating the...
3.
Joyce M, Bu W, Chen W, Gillespie R, Andrews S, Wheatley A, et al.
Immunity
. 2025 Feb;
58(2):295-308.e5.
PMID: 39909035
Epstein-Barr virus (EBV) causes infectious mononucleosis and is associated with malignancies in humans. Viral infection of B cells is initiated by the viral glycoprotein 350 (gp350) binding to complement receptor...
4.
Mantus G, Chopde A, Gorman J, Cominsky L, Ourahmane A, Creanga A, et al.
Sci Transl Med
. 2025 Jan;
17(779):eadr8373.
PMID: 39742506
The conserved influenza hemagglutinin stem, which is a target of cross-neutralizing antibodies, is now used in vaccine strategies focused on protecting against influenza pandemics. Antibody responses to group 1 stem...
5.
Lederhofer J, Borst A, Nguyen L, Gillespie R, Williams C, Walker E, et al.
bioRxiv
. 2024 Dec;
PMID: 39677750
Influenza has been responsible for multiple global pandemics and seasonal epidemics and claimed millions of lives. The imminent threat of a panzootic outbreak of avian influenza H5N1 virus underscores the...
6.
Lemos M, Astronomo R, Huang Y, Narpala S, Prabhakaran M, Mann P, et al.
Nat Commun
. 2024 Nov;
15(1):10332.
PMID: 39609400
To prevent sexually-acquired HIV-1 infection by immunoprophylaxis, effective concentrations of broadly neutralizing antibodies are likely needed at mucosal sites of exposure. Here, we examine the biodistribution of monoclonal antibody VRC01...
7.
Carpp L, Hyrien O, Fong Y, Benkeser D, Roels S, Stieh D, et al.
Nat Commun
. 2024 Nov;
15(1):9785.
PMID: 39532861
Assessment of immune correlates of severe COVID-19 has been hampered by the low numbers of severe cases in COVID-19 vaccine efficacy (VE) trials. We assess neutralizing and binding antibody levels...
8.
Casazza J, Hofstetter A, Costner P, Holman L, Hendel C, Widge A, et al.
NPJ Vaccines
. 2024 Sep;
9(1):171.
PMID: 39289377
The relative conservation of the influenza hemagglutinin (HA) stem compared to that of the immunodominant HA head makes the HA stem an attractive target for broadly protective influenza vaccines. Here...
9.
Julg B, Walker-Sperling V, Wagh K, Aid M, Stephenson K, Zash R, et al.
Nat Med
. 2024 Sep;
30(12):3534-3543.
PMID: 39266747
Human immunodeficiency virus type 1 (HIV-1)-specific broadly neutralizing monoclonal antibodies (bNAbs) have to date shown transient viral suppression when administered as monotherapy or as a cocktail of two antibodies. A...
10.
Caniels T, Medina-Ramirez M, Zhang S, Kratochvil S, Xian Y, Koo J, et al.
Sci Immunol
. 2024 Aug;
9(98):eadk9550.
PMID: 39213338
Eliciting potent and broadly neutralizing antibodies (bnAbs) is a major goal in HIV-1 vaccine development. Here, we describe how germline-targeting immunogen BG505 SOSIP germline trimer 1.1 (GT1.1), generated through structure-based...