Adam Pruska
Overview
Explore the profile of Adam Pruska including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
36
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0
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Recent Articles
1.
Harrison J, Gabriel J, Pruska A, Zenobi R
Anal Chem
. 2024 Nov;
96(48):18932-18938.
PMID: 39556209
Solution and gas-phase measurements can provide valuable insights into biomolecular conformational dynamics. By comparing the data from such experiments, it is possible to elucidate the nature of the interactions governing...
2.
Zdanowicz R, Afanasyev P, Pruska A, Harrison J, Giese C, Boehringer D, et al.
Sci Adv
. 2024 Jul;
10(29):eadn4582.
PMID: 39018392
The pyruvate dehydrogenase complex (PDHc) is a key megaenzyme linking glycolysis with the citric acid cycle. In mammalian PDHc, dihydrolipoamide acetyltransferase (E2) and the dihydrolipoamide dehydrogenase-binding protein (E3BP) form a...
3.
Pruska A, Harrison J, Granzhan A, Marchand A, Zenobi R
Anal Chem
. 2023 Sep;
95(38):14384-14391.
PMID: 37699589
DNA three-way junction (TWJ) structures transiently form during key cellular processes such as transcription, replication, and DNA repair. Despite their significance, the thermodynamics of TWJs, including the influence of strand...
4.
Nydegger M, Pruska A, Galinski H, Zenobi R, Reiser A, Spolenak R
Nanoscale
. 2022 Nov;
14(46):17418-17427.
PMID: 36385575
Electrohydrodynamic redox 3D printing (EHD-RP) is an additive manufacturing (AM) technique with submicron resolution and multi-metal capabilities, offering the possibility to switch chemistry during deposition "on-the-fly". Despite the potential for...
5.
Harrison J, Pruska A, Bittner P, Muck A, Cooper-Shepherd D, Zenobi R
Anal Chem
. 2022 Sep;
94(36):12435-12443.
PMID: 36049221
Native mass spectrometry is a powerful tool for the analysis of noncovalent complexes. When coupled with high-resolution ion mobility, this technique can be used to investigate the conformational changes induced...
6.
Martinez-Jarquin S, Begley A, Lai Y, Bartolomeo G, Pruska A, Rotach C, et al.
Anal Chem
. 2022 Mar;
94(14):5651-5657.
PMID: 35343676
We tested a paper-based platform ("Aptapaper") for the upconcentration and analysis of small molecules from complex matrices for two well-characterized aptamers, quinine and serotonin binding aptamers (QBA and SBA, respectively)....
7.
Alexander Harrison J, Pruska A, Oganesyan I, Bittner P, Zenobi R
Chemistry
. 2021 Oct;
27(72):18015-18028.
PMID: 34632657
Native electrospray ionization (ESI) and nanoelectrospray ionization (nESI) allow researchers to analyze intact biomolecules and their complexes by mass spectrometry (MS). The data acquired using these soft ionization techniques provide...
8.
Hagen T, Laski A, Brummer A, Pruska A, Schlosser V, Clery A, et al.
J Am Chem Soc
. 2021 Sep;
143(37):15120-15130.
PMID: 34520206
It is well-accepted that gene expression is heavily influenced by RNA structure. For instance, stem-loops and G-quadruplexes (rG4s) are dynamic motifs in mRNAs that influence gene expression. Adenosine-to-inosine (A-to-I) editing...
9.
Pruska A, Marchand A, Zenobi R
Angew Chem Int Ed Engl
. 2021 Apr;
60(28):15390-15398.
PMID: 33822450
Quadruplexes are non-canonical nucleic acid structures essential for many cellular processes. Hybrid quadruplex-duplex oligonucleotide assemblies comprised of multiple domains are challenging to study with conventional biophysical methods due to their...
10.
Pavlatovska B, Machalkova M, Brisudova P, Pruska A, Stepka K, Michalek J, et al.
Front Oncol
. 2020 Dec;
10:581365.
PMID: 33344237
Colorectal cancer (CRC) is a disease with constantly increasing incidence and high mortality. The treatment efficacy could be curtailed by drug resistance resulting from poor drug penetration into tumor tissue...