Adam M Syanda
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Explore the profile of Adam M Syanda including associated specialties, affiliations and a list of published articles.
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4
Citations
16
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Recent Articles
1.
Kent D, Ng S, Syanda A, Khoshkenar P, Ronzoni R, Li C, et al.
Hepatology
. 2024 Jul;
81(3):903-916.
PMID: 38954820
Background: Alpha-1 antitrypsin deficiency (A1ATD) is a life-threatening condition caused by the inheritance of the serpin family A member 1 "Z" genetic variant driving alpha-1 antitrypsin (AAT) protein misfolding in...
2.
Blackford S, Yu T, Norman M, Syanda A, Manolakakis M, Lachowski D, et al.
Biomaterials
. 2023 Jan;
293:121982.
PMID: 36640555
Human pluripotent stem cell-derived hepatocytes (hPSC-Heps) may be suitable for treating liver diseases, but differentiation protocols often fail to yield adult-like cells. We hypothesised that replicating healthy liver niche biochemical...
3.
Syanda A, Kringstad V, Blackford S, Kjesbu J, Ng S, Ma L, et al.
Front Bioeng Biotechnol
. 2022 Mar;
9:816542.
PMID: 35308825
Intra-peritoneal placement of alginate encapsulated human induced pluripotent stem cell-derived hepatocytes (hPSC-Heps) represents a potential new bridging therapy for acute liver failure. One of the rate-limiting steps that needs to...
4.
Li C, Ogawa H, Ng S, Chen X, Kishimoto E, Sakabe K, et al.
JHEP Rep
. 2022 Mar;
4(4):100446.
PMID: 35284810
Background & Aims: The truncating mutations in tight junction protein 2 (TJP2) cause progressive cholestasis, liver failure, and hepatocyte carcinogenesis. Due to the lack of effective model systems, there are...