Adam G Hendricks
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Explore the profile of Adam G Hendricks including associated specialties, affiliations and a list of published articles.
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25
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719
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Recent Articles
11.
Cario A, Savastano A, Wood N, Liu Z, Previs M, Hendricks A, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(7).
PMID: 35135879
The microtubule-associated protein (MAP) Tau is an intrinsically disordered protein (IDP) primarily expressed in axons, where it functions to regulate microtubule dynamics, modulate motor protein motility, and participate in signaling...
12.
Bergeron-Sandoval L, Kumar S, Heris H, Chang C, Cornell C, Keller S, et al.
Proc Natl Acad Sci U S A
. 2021 Dec;
118(50).
PMID: 34887356
Membrane invagination and vesicle formation are key steps in endocytosis and cellular trafficking. Here, we show that endocytic coat proteins with prion-like domains (PLDs) form hemispherical puncta in the budding...
13.
Chaubet L, Chaudhary A, Heris H, Ehrlicher A, Hendricks A
Mol Biol Cell
. 2020 Jun;
31(16):1744-1752.
PMID: 32579489
Cells precisely control their mechanical properties to organize and differentiate into tissues. The architecture and connectivity of cytoskeletal filaments change in response to mechanical and biochemical cues, allowing the cell...
14.
Chaudhary A, Lu H, Krementsova E, Bookwalter C, Trybus K, Hendricks A
J Biol Chem
. 2019 May;
294(26):10160-10171.
PMID: 31085585
Microtubule-associated proteins (MAPs) regulate microtubule polymerization, dynamics, and organization. In addition, MAPs alter the motility of kinesin and dynein to control trafficking along microtubules. MAP7 (ensconsin, E-MAP-115) is a ubiquitous...
15.
Chaudhary A, Berger F, Berger C, Hendricks A
Traffic
. 2017 Oct;
19(2):111-121.
PMID: 29077261
Organelles, proteins, and mRNA are transported bidirectionally along microtubules by plus-end directed kinesin and minus-end directed dynein motors. Microtubules are decorated by microtubule-associated proteins (MAPs) that organize the cytoskeleton, regulate...
16.
Balabanian L, Berger C, Hendricks A
Biophys J
. 2017 Oct;
113(7):1551-1560.
PMID: 28978447
The motor proteins kinesin and dynein transport organelles, mRNA, proteins, and signaling molecules along the microtubule cytoskeleton. In addition to serving as tracks for transport, the microtubule cytoskeleton directs intracellular...
17.
Yogev S, Maeder C, Cooper R, Horowitz M, Hendricks A, Shen K
Nat Commun
. 2017 Apr;
8:15063.
PMID: 28406181
Abnormal axonal transport is associated with neuronal disease. We identified a role for DHC-1, the C. elegans dynein heavy chain, in maintaining neuronal cargo distribution. Surprisingly, this does not involve...
18.
Hendricks A, Goldman Y
Methods Mol Biol
. 2016 Nov;
1486:537-552.
PMID: 27844443
Optical tweezers have been instrumental in uncovering the mechanisms motor proteins use to generate and react to force. While optical traps have primarily been applied to purified, in vitro systems,...
19.
Hendricks A, Goldman Y, Holzbaur E
Methods Enzymol
. 2014 Mar;
540:249-62.
PMID: 24630111
Kinesin, dynein, and myosin transport intracellular cargoes including organelles, membrane-bound vesicles, and mRNA along the cytoskeleton. These motor proteins work collectively in teams to transport cargoes over long distances and...
20.
Perlson E, Hendricks A, Lazarus J, Ben-Yaakov K, Gradus T, Tokito M, et al.
J Biol Chem
. 2013 Aug;
288(39):27812-24.
PMID: 23960070
Cytoplasmic dynein is well characterized as an organelle motor, but dynein also acts to tether and stabilize dynamic microtubule plus-ends in vitro. Here we identify a novel and direct interaction...