Adam D Ewing
Overview
Explore the profile of Adam D Ewing including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
43
Citations
2321
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kleynhans L, Kunsevi-Kilola C, Tshivhula H, Webber T, Keyser A, Prins N, et al.
Res Sq
. 2024 Dec;
PMID: 39649174
Type 2 diabetes (T2D) increases susceptibility to tuberculosis (TB) with the underlying mechanisms remaining unknown. To determine whether immune dysfunction in the lung contributes to TB susceptibility, we obtained paired...
2.
Demetriou K, Nisbet J, Coman D, Ewing A, Phillips L, Smith S, et al.
Mol Genet Metab
. 2024 Jun;
142(4):108516.
PMID: 38941880
Glutaric aciduria type II (GAII) is a heterogeneous genetic disorder affecting mitochondrial fatty acid, amino acid and choline oxidation. Clinical manifestations vary across the lifespan and onset may occur at...
3.
Bodea G, Botto J, Ferreiro M, Sanchez-Luque F, de Los Rios Barreda J, Rasmussen J, et al.
Nat Neurosci
. 2024 May;
27(7):1274-1284.
PMID: 38773348
Retrotransposons are mobile DNA sequences duplicated via transcription and reverse transcription of an RNA intermediate. Cis-regulatory elements encoded by retrotransposons can also promote the transcription of adjacent genes. Somatic LINE-1...
4.
Gerdes P, Chan D, Lundberg M, Sanchez-Luque F, Bodea G, Ewing A, et al.
Genome Res
. 2023 Oct;
33(9):1465-1481.
PMID: 37798118
Mice harbor ∼2800 intact copies of the retrotransposon Long Interspersed Element 1 (L1). The in vivo retrotransposition capacity of an L1 copy is defined by both its sequence integrity and...
5.
Gerdes P, Lim S, Ewing A, Larcombe M, Chan D, Sanchez-Luque F, et al.
Nat Commun
. 2022 Dec;
13(1):7470.
PMID: 36463236
Induced pluripotent stem cells (iPSCs) can in principle differentiate into any cell of the body, and have revolutionized biomedical research and regenerative medicine. Unlike their human counterparts, mouse iPSCs (miPSCs)...
6.
Burgess M, Keane C, Tobin J, Law S, Griffin A, Gill D, et al.
Acta Haematol
. 2022 Oct;
146(2):166-171.
PMID: 36273464
Here, we present a novel case of a patient with chronic lymphocytic leukemia (CLL) who received CTLA-4 and then PD-1 immune-checkpoint blockade (ICB) as treatment for concomitant metastatic melanoma. Whereas...
7.
Billon V, Sanchez-Luque F, Rasmussen J, Bodea G, Gerhardt D, Gerdes P, et al.
Genome Res
. 2022 Jun;
32(7):1298-1314.
PMID: 35728967
The retrotransposon LINE-1 (L1) is central to the recent evolutionary history of the human genome and continues to drive genetic diversity and germline pathogenesis. However, the spatiotemporal extent and biological...
8.
Cheetham S, Kindlova M, Ewing A
Bioinformatics
. 2022 Apr;
38(11):3109-3112.
PMID: 35482479
Summary: Methylartist is a consolidated suite of tools for processing, visualizing and analysing nanopore-derived modified base calls. All detectable methylation types (e.g. 5mCpG, 5hmC, 6mA) are supported, enabling integrated study...
9.
van Bree E, Guimaraes R, Lundberg M, Blujdea E, Rosenkrantz J, White F, et al.
Genome Res
. 2022 Mar;
32(4):656-670.
PMID: 35332097
Genome-wide association studies (GWAS) have been highly informative in discovering disease-associated loci but are not designed to capture all structural variations in the human genome. Using long-read sequencing data, we...
10.
Rasmussen J, Ewing A, Bodea L, Bodea G, Gearing M, Faulkner G
Brain Pathol
. 2021 Aug;
32(3):e13018.
PMID: 34463402
Age is one of the strongest risk factors for the development of neurodegenerative diseases, the majority of which involve misfolded protein aggregates in the brain. These protein aggregates are thought...