Adam D Bachstetter
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Explore the profile of Adam D Bachstetter including associated specialties, affiliations and a list of published articles.
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77
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3511
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Recent Articles
1.
Shahidehpour R, Nelson P, Srinivasan S, Yu Z, Bachstetter A
Neuropathology
. 2025 Mar;
PMID: 40042444
Mutations in the Integral membrane protein 2B (ITM2B) gene are linked to the development of familial British and Danish dementias, two relatively early-onset dementia disorders known also to be associated...
2.
Macheda T, Andres M, Sanders L, Roberts K, Shahidehpour R, Morganti J, et al.
Neurotrauma Rep
. 2024 Aug;
5(1):770-786.
PMID: 39184175
The increasing incidence of traumatic brain injury (TBI) among older adults, particularly mild injuries from falls, underscores the need to investigate age-related outcomes and potential sex differences in response to...
3.
Shahidehpour R, Nelson P, Katsumata Y, Bachstetter A
Brain
. 2024 Aug;
148(1):89-101.
PMID: 39101580
Genetics and other data modalities indicate that microglia play a critical role in Alzheimer's disease progression, but details of the disease-driving influence of microglia are poorly understood. Microglial cells can...
4.
Shahidehpour R, Nelson P, Bachstetter A
Acta Neuropathol Commun
. 2024 Jul;
12(1):114.
PMID: 38997773
Background: TAR DNA-Binding Protein 43 (TDP-43) pathological inclusions are a distinctive feature in dozens of neurodegenerative pathologies, including limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC). Prior investigations identified vascular-associated TDP-43-positive...
5.
Winford E, Lutshumba J, Martin B, Wilcock D, Jicha G, Nikolajczyk B, et al.
Immun Ageing
. 2024 Jun;
21(1):36.
PMID: 38867294
Background And Purpose: The immune response changes during aging and the progression of Alzheimer's disease (AD) and related dementia (ADRD). Terminally differentiated effector memory T cells (called T) are important...
6.
Wilson J, Kigerl K, Sunshine M, Taylor C, Speed S, Rose B, et al.
bioRxiv
. 2024 Jan;
PMID: 38187534
Research Highlights: Cervical spinal cord injury (SCI) causes transient gut dysbiosis and persistent gastrointestinal (GI) pathology.Treatment with probiotics after SCI leads to a healthier GI tract and improved respiratory motor...
7.
Winford E, Lutshumba J, Martin B, Wilcock D, Jicha G, Nikolajczyk B, et al.
bioRxiv
. 2023 Dec;
PMID: 38077088
Background And Purpose: The immune response changes during aging and the progression of Alzheimer's disease (AD) and related dementia (ADRD). Terminally differentiated effector memory T cells (called TEMRA) are important...
8.
Vincent J, Garnett C, Watson J, Higgins E, Macheda T, Sanders L, et al.
J Neuroinflammation
. 2023 Dec;
20(1):287.
PMID: 38037111
No abstract available.
9.
Bachstetter A, Lutshumba J, Winford E, Abner E, Martin B, Harp J, et al.
Brain Commun
. 2023 Oct;
5(5):fcad259.
PMID: 37901041
People with dementia have an increase in brain inflammation, caused in part by innate and adaptive immune cells. However, it remains unknown whether dementia-associated diseases alter neuro-immune reflex arcs to...
10.
Vincent J, Garnett C, Watson J, Higgins E, Macheda T, Sanders L, et al.
J Neuroinflammation
. 2023 Oct;
20(1):248.
PMID: 37884959
Neuroinflammation contributes to secondary injury cascades following traumatic brain injury (TBI), with alternating waves of inflammation and resolution. Interleukin-1 (IL-1), a critical neuroinflammatory mediator originating from brain endothelial cells, microglia,...