Adam Cantlon
Overview
Explore the profile of Adam Cantlon including associated specialties, affiliations and a list of published articles.
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7
Citations
343
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Recent Articles
1.
De Boni L, Watson A, Zaccagnini L, Wallis A, Zhelcheska K, Kim N, et al.
Acta Neuropathol
. 2022 Feb;
143(4):453-469.
PMID: 35141810
The protein α-synuclein, a key player in Parkinson's disease (PD) and other synucleinopathies, exists in different physiological conformations: cytosolic unfolded aggregation-prone monomers and helical aggregation-resistant multimers. It has been shown...
2.
El Fatimy R, Li S, Chen Z, Mushannen T, Gongala S, Wei Z, et al.
Acta Neuropathol
. 2018 Jul;
136(4):537-555.
PMID: 29982852
MicroRNAs (miRNA) regulate fundamental biological processes, including neuronal plasticity, stress response, and survival. Here, we describe a neuroprotective function of miR-132, the miRNA most significantly downregulated in neurons in Alzheimer's...
3.
Sarosiek K, Fraser C, Muthalagu N, Bhola P, Chang W, McBrayer S, et al.
Cancer Cell
. 2016 Dec;
31(1):142-156.
PMID: 28017613
It is not understood why healthy tissues can exhibit varying levels of sensitivity to the same toxic stimuli. Using BH3 profiling, we find that mitochondria of many adult somatic tissues,...
4.
Cantlon A, Sala Frigerio C, Walsh D
J Parkinsons Dis Alzheimers Dis
. 2015 Sep;
2(1).
PMID: 26405694
Here we review the similarities between a rare inherited disorder, familial British dementia (FBD), and the most common of all late-life neurological conditions, Alzheimer's diseases (AD). We describe the symptoms,...
5.
Kanmert D, Cantlon A, Muratore C, Jin M, OMalley T, Lee G, et al.
J Neurosci
. 2015 Jul;
35(30):10851-65.
PMID: 26224867
Significance Statement: Recent studies suggest that the transfer of tau between neurons underlies the characteristic spatiotemporal progression of neurofibrillary pathology. We searched for tau in the conditioned medium of N2a...
6.
Guan Y, Cao K, Cantlon A, Elbel K, Theodorakis E, Walsh D, et al.
ACS Chem Neurosci
. 2015 Jul;
6(9):1503-8.
PMID: 26212450
This work describes the use of fluorescence correlation spectroscopy (FCS) and a novel amyloid-binding fluorescent probe, ARCAM 1, to monitor the aggregation of the Alzheimer's disease-associated amyloid β-peptide (Aβ). ARCAM...
7.
Cantlon A, Sala Frigerio C, Freir D, Boland B, Jin M, Walsh D
J Biol Chem
. 2015 May;
290(27):16502-16.
PMID: 25957407
Familial British dementia (FBD) is an inherited neurodegenerative disease believed to result from a mutation in the BRI2 gene. Post-translational processing of wild type BRI2 and FBD-BRI2 result in the...