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Adam B Salmon

Explore the profile of Adam B Salmon including associated specialties, affiliations and a list of published articles. Areas
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Articles 89
Citations 3965
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Recent Articles
31.
Dorigatti J, Thyne K, Ginsburg B, Salmon A
Biochem Biophys Rep . 2021 Jun; 27:101040. PMID: 34141906
Activation of AMP activated protein kinase (AMPK) signaling has been demonstrated to extend lifespan and improve healthspan across multiple species. This suggests pharmaceutical approaches to increase AMPK hold the potential...
32.
Lee H, Donati A, Feliers D, Sun Y, Ding Y, Madesh M, et al.
Aging Cell . 2021 Jun; 20(7):e13407. PMID: 34118180
The mechanism of kidney injury in aging are not well understood. In order to identify hitherto unknown pathways of aging-related kidney injury, we performed RNA-Seq on kidney extracts of young...
33.
Adekunbi D, Li C, Nathanielsz P, Salmon A
Geroscience . 2021 Jun; 43(4):2067-2085. PMID: 34089175
Aging is associated with progressive loss of cellular homeostasis resulting from intrinsic and extrinsic challenges. Lack of a carefully designed, well-characterized, precise, translational experimental model is a major limitation to...
34.
Dorigatti J, Thyne K, Ginsburg B, Salmon A
Geroscience . 2021 Apr; 43(3):1497-1511. PMID: 33890206
AMP-activated protein kinase (AMPK) is a central regulator of both lifespan and health across multiple model organisms. β-Guanidinopropionic acid (GPA) is an endogenous AMPK activator previously shown to improve metabolic...
35.
Bhattacharya A, Pulliam D, Liu Y, Salmon A
Aging Pathobiol Ther . 2021 Apr; 2(1):45-51. PMID: 33829213
Objective: Mitochondrial dysfunction comprises part of the etiology of myriad health issues, particularly those that occur with advancing age. Methionine sulfoxide reductase A (MsrA) is a ubiquitous protein oxidation repair...
36.
Ross C, Salmon A
Nutr Healthy Aging . 2021 Apr; 5(2):97-109. PMID: 33817407
Traditional animal models have been used to make seminal discoveries in biomedical research including a better understanding of the biology of the aging process. However, translation of these findings from...
37.
Strong R, Miller R, Bogue M, Fernandez E, Javors M, Libert S, et al.
Aging Cell . 2020 Nov; 19(11):e13269. PMID: 33145977
To see if variations in timing of rapamycin (Rapa), administered to middle aged mice starting at 20 months, would lead to different survival outcomes, we compared three dosing regimens. Initiation...
38.
Dorigatti A, Hussong S, Hernandez S, Sills A, Salmon A, Galvan V
Geroscience . 2020 Oct; 43(1):115-124. PMID: 33063253
The ability to generate in vitro cultures of neuronal cells has been instrumental in advancing our understanding of the nervous system. Rodent models have been the principal source of brain...
39.
Miller R, Harrison D, Allison D, Bogue M, Debarba L, Diaz V, et al.
JCI Insight . 2020 Sep; 5(21). PMID: 32990681
Canagliflozin (Cana) is an FDA-approved diabetes drug that protects against cardiovascular and kidney diseases. It also inhibits the sodium glucose transporter 2 by blocking renal reuptake and intestinal absorption of...
40.
Lamming D, Salmon A
J Gerontol A Biol Sci Med Sci . 2019 Sep; 75(1):1-3. PMID: 31544928
No abstract available.