Abdul Aziz Mohamed Yusoff
Overview
Explore the profile of Abdul Aziz Mohamed Yusoff including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
161
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0
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Recent Articles
11.
Abd Radzak S, Mohd Khair S, Ahmad F, Patar A, Idris Z, Yusoff A
Int J Mol Med
. 2022 Jun;
50(2).
PMID: 35713211
Mitochondria are the critical organelles involved in various cellular functions. Mitochondrial biogenesis is activated by multiple cellular mechanisms which require a synchronous regulation between mitochondrial DNA (mtDNA) and nuclear DNA...
12.
Yusoff A, Abd Radzak S, Mohd Khair S
Contemp Oncol (Pozn)
. 2022 May;
26(1):8-26.
PMID: 35506039
Cancer has been broadly considered a genetic disease involving mutations in nuclear DNA and the mitochondrial genome (mtDNA). Mitochondria are essential bioenergetics and biosynthetic machinery found in most eukaryotic organisms....
13.
Hassan S, Yusoff A, Idris Z, Mohd Redzwan N, Ahmad F
Neurol Res
. 2021 Sep;
44(3):242-251.
PMID: 34533110
Background: Previous studies had reported on the cytotoxic activities of generic antibiotics such as doxycycline (DOXY) and azithromycin (AZI) in multiple types of human cancers. Given that resistance to standard...
14.
Mohd Khair S, Abd Radzak S, Yusoff A
Dis Markers
. 2021 Jul;
2021:7675269.
PMID: 34326906
Cancer is a heterogeneous group of diseases, the progression of which demands an accumulation of genetic mutations and epigenetic alterations of the human nuclear genome or possibly in the mitochondrial...
15.
Zakaria N, Islam M, Abdullah W, Bahar R, Yusoff A, Abdul Wahab R, et al.
Biomolecules
. 2021 Jun;
11(5).
PMID: 34070036
Thalassemia, an inherited quantitative globin disorder, consists of two types, α- and -thalassemia. -thalassemia is a heterogeneous disease that can be asymptomatic, mild, or even severe. Considerable research has focused...
16.
Yusoff A, Mohd Khair S, Wan Abdullah W, Abd Radzak S, Abdullah J
J Cancer Res Ther
. 2020 Dec;
16(6):1517-1521.
PMID: 33342822
Background And Objective: Meningiomas are among the most common intracranial tumors of the central nervous system. It is widely accepted that the initiation and progression of meningiomas involve the accumulation...
17.
Yusoff A, Mohd Khair S, Abd Radzak S, Idris Z, Lee H
J Chin Med Assoc
. 2020 Aug;
83(9):838-844.
PMID: 32732530
Background: The 4977-bp common deletion (mtDNA) is a well-established mitochondrial genome alteration that has been described in various types of human cancers. However, to date, no studies on mtDNA in...
18.
Mohd Khair S, Ismail A, Embong Z, Yusoff A
J Ophthalmic Vis Res
. 2019 May;
14(2):171-178.
PMID: 31114654
Purpose: To determine the mutational analyses of familial exudative vitreoretinopathy (FEVR)-causing genes in Malay patients with retinopathy of prematurity (ROP) to obtain preliminary data for gene alterations in the Malay...
19.
Yusoff A, Wan Abdullah W, Mohd Khair S, Abd Radzak S
Oncol Rev
. 2019 May;
13(1):409.
PMID: 31044027
Mitochondria are cellular machines essential for energy production. The biogenesis of mitochondria is a highly complex and it depends on the coordination of the nuclear and mitochondrial genome. Mitochondrial DNA...
20.
Chong P, Sangu M, Jong Huat T, Reza F, Begum T, Yusoff A, et al.
Malays J Med Sci
. 2019 Mar;
25(6):28-45.
PMID: 30914877
Background: Following brain injury, development of hippocampal sclerosis often led to the temporal lobe epilepsy which is sometimes resistant to common anti-epileptic drugs. Cellular and molecular changes underlying epileptogenesis in...