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Abdelghani Mazouzi

Explore the profile of Abdelghani Mazouzi including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 382
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11.
Mazouzi A, Velimezi G, Loizou J
Exp Cell Res . 2014 Oct; 329(1):85-93. PMID: 25281304
DNA replication is a fundamental process of the cell that ensures accurate duplication of the genetic information and subsequent transfer to daughter cells. Various pertubations, originating from endogenous or exogenous...
12.
Wang Z, Ayoub E, Mazouzi A, Grin I, Ishchenko A, Fan J, et al.
DNA Repair (Amst) . 2014 Aug; 22:53-66. PMID: 25108836
Human APE1 is an essential enzyme performing functions in DNA repair and transcription. It possesses four distinct repair activities acting on a variety of base and sugar derived DNA lesions....
13.
Mazouzi A, Vigouroux A, Aikeshev B, Brooks P, Saparbaev M, Morera S, et al.
Proc Natl Acad Sci U S A . 2013 Jul; 110(33):E3071-80. PMID: 23898172
8,5'-cyclo-2'-deoxyadenosine (cdA) and 8,5'-cyclo-2'-deoxyguanosine generated in DNA by both endogenous oxidative stress and ionizing radiation are helix-distorting lesions and strong blocks for DNA replication and transcription. In duplex DNA, these...
14.
Redrejo-Rodriguez M, Saint-Pierre C, Couve S, Mazouzi A, Ishchenko A, Gasparutto D, et al.
PLoS One . 2011 Jul; 6(7):e21039. PMID: 21799731
Background: Oxidative damage to DNA, if not repaired, can be both miscoding and blocking. These genetic alterations can lead to mutations and/or cell death, which in turn cause cancer and...