Jana Prochazkova
Overview
Explore the profile of Jana Prochazkova including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
264
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Recent Articles
1.
Ashraf R, Polasek-Sedlackova H, Marini V, Prochazkova J, Hasanova Z, Zacpalova M, et al.
Nat Commun
. 2025 Feb;
16(1):1302.
PMID: 39900600
Replication stress, particularly in hard-to-replicate regions such as telomeres and centromeres, leads to the accumulation of replication intermediates that must be processed to ensure proper chromosome segregation. In this study,...
2.
Nikulenkov F, Carbain B, Biswas R, Havel S, Prochazkova J, Sisakova A, et al.
Eur J Med Chem
. 2025 Jan;
285:117226.
PMID: 39793442
MRE11 nuclease is a central player in signaling and processing DNA damage, and in resolving stalled replication forks. Here, we describe the identification and characterization of new MRE11 inhibitors MU147...
3.
Ocovska Z, Prochazkova J, Marikova M, Vlcek J
Expert Opin Drug Saf
. 2024 Feb;
23(4):457-467.
PMID: 38332533
Background: The study aimed to evaluate the agreement of prescribed drug dosages with renal dosing recommendations and describe adverse drug events (ADEs) contributing to hospital admissions of patients with chronic...
4.
Bradacova P, Slavik L, Ulehlova J, Kriegova E, Jara E, Bultasova L, et al.
Biomedicines
. 2023 Dec;
11(12).
PMID: 38137550
The aim of this study was to determine the thrombogenicity of lupus anticoagulant (LA) antibodies using a modified thrombin generation assay (TGA) with the addition of activated protein C (APC)...
5.
Bradacova P, Slavik L, Skoumalova A, Ulehlova J, Kriegova E, Manukyan G, et al.
Int J Mol Sci
. 2022 Aug;
23(16).
PMID: 36012233
Antiphospholipid syndrome (APS) is a hypercoagulable state accompanied by the presence of heterogeneous antiphospholipid antibodies (aPL), which nonspecifically affect hemostasis by the presence of lupus anticoagulans (LA), anticardiolipin antibodies (aCL),...
6.
Vrtel P, Slavik L, Vodicka R, Stellmachova J, Prochazka M, Prochazkova J, et al.
Diagnostics (Basel)
. 2022 May;
12(5).
PMID: 35626216
The deficiency of natural anticoagulants—antithrombin (AT), protein C (PC), and protein S (PS)—is a highly predisposing factor for thrombosis, which is still underdiagnosed at the genetic level. We aimed to...
7.
Ulehlova J, Pisklakova B, Ivanovova E, Prochazkova J, Bradacova P, Kvasnicka A, et al.
Diagnostics (Basel)
. 2021 Nov;
11(11).
PMID: 34829374
Background: The effect of direct oral anticoagulants (DOAC) on laboratory tests dependent on the production of their targets, factor IIa and factor Xa, is a well-known problem and can cause...
8.
Bradacova P, Slavik L, Ulehlova J, Skoumalova A, Ullrychova J, Prochazkova J, et al.
Biomedicines
. 2021 Feb;
9(2).
PMID: 33567576
Antiphospholipid syndrome (APS) is a hypercoagulation condition associated with the incidence of heterogenic antiphospholipid antibodies (aPLs), which non-specifically affect hemostasis processes. APS is clinically manifested by recurrent arterial and venous...
9.
Stefanovie B, Hengel S, Mlcouskova J, Prochazkova J, Spirek M, Nikulenkov F, et al.
Nucleic Acids Res
. 2019 Dec;
48(2):694-708.
PMID: 31799622
The proper repair of deleterious DNA lesions such as double strand breaks prevents genomic instability and carcinogenesis. In yeast, the Rad52 protein mediates DSB repair via homologous recombination. In mammalian...
10.
Maurer B, Nivarthi H, Wingelhofer B, Pham H, Schlederer M, Suske T, et al.
Haematologica
. 2019 May;
105(2):435-447.
PMID: 31123029
Recurrent gain-of-function mutations in the transcription factors and much more in were found in hematopoietic malignancies with the highest proportion in mature T- and natural killer-cell neoplasms (peripheral T-cell lymphoma,...