Aaron Weimann
Overview
Explore the profile of Aaron Weimann including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
746
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0
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Recent Articles
1.
Figueroa W, Cazares A, Ashworth E, Weimann A, Kadioglu A, Floto R, et al.
Cell Rep
. 2024 Dec;
44(1):115079.
PMID: 39708318
Pseudomonas aeruginosa produces a wealth of virulence factors whose production is controlled via an intricate regulatory systems network. Here, we uncover a major player in the evolution and regulation of...
2.
Evans I, Weimann A, Baird T, Haworth C, Floto A
J Cyst Fibros
. 2024 Jul;
PMID: 39068106
No abstract available.
3.
Weimann A, Dinan A, Ruis C, Bernut A, Pont S, Brown K, et al.
Science
. 2024 Jul;
385(6704):eadi0908.
PMID: 38963857
The major human bacterial pathogen causes multidrug-resistant infections in people with underlying immunodeficiencies or structural lung diseases such as cystic fibrosis (CF). We show that a few environmental isolates, driven...
4.
Ruis C, Weimann A, Tonkin-Hill G, Pandurangan A, Matuszewska M, Murray G, et al.
Nat Commun
. 2023 Nov;
14(1):7091.
PMID: 37925514
As observed in cancers, individual mutagens and defects in DNA repair create distinctive mutational signatures that combine to form context-specific spectra within cells. We reasoned that similar processes must occur...
5.
On Y, Figueroa W, Fan C, Ho P, Benyei E, Weimann A, et al.
ISME J
. 2023 Sep;
17(11):1931-1939.
PMID: 37666975
Once acquired, hypermutation is unrelenting, and in the long-term, leads to impaired fitness due to its cumulative impact on the genome. This raises the question of why hypermutators arise so...
6.
Boeck L, Burbaud S, Skwark M, Pearson W, Sangen J, Wuest A, et al.
Nat Microbiol
. 2022 Aug;
7(9):1431-1441.
PMID: 36008617
The medical and scientific response to emerging and established pathogens is often severely hampered by ignorance of the genetic determinants of virulence, drug resistance and clinical outcomes that could be...
7.
Bryant J, Brown K, Burbaud S, Everall I, Belardinelli J, Rodriguez-Rincon D, et al.
Science
. 2021 Apr;
372(6541).
PMID: 33926925
Although almost all mycobacterial species are saprophytic environmental organisms, a few, such as , have evolved to cause transmissible human infection. By analyzing the recent emergence and spread of the...
8.
9.
Tonkin-Hill G, MacAlasdair N, Ruis C, Weimann A, Horesh G, Lees J, et al.
Genome Biol
. 2020 Jul;
21(1):180.
PMID: 32698896
Population-level comparisons of prokaryotic genomes must take into account the substantial differences in gene content resulting from horizontal gene transfer, gene duplication and gene loss. However, the automated annotation of...
10.
Khaledi A, Weimann A, Schniederjans M, Asgari E, Kuo T, Oliver A, et al.
EMBO Mol Med
. 2020 Feb;
12(3):e10264.
PMID: 32048461
Limited therapy options due to antibiotic resistance underscore the need for optimization of current diagnostics. In some bacterial species, antimicrobial resistance can be unambiguously predicted based on their genome sequence....