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Aaron M Gibson

Explore the profile of Aaron M Gibson including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 808
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Recent Articles
21.
Le Cras T, Acciani T, Mushaben E, Kramer E, Pastura P, Hardie W, et al.
Am J Physiol Lung Cell Mol Physiol . 2011 Jan; 300(3):L414-21. PMID: 21224214
Increases in the epidermal growth factor receptor (EGFR) have been associated with the severity of airway thickening in chronic asthmatic subjects, and EGFR signaling is induced by asthma-related cytokines and...
22.
Sivaprasad U, Askew D, Ericksen M, Gibson A, Stier M, Brandt E, et al.
J Allergy Clin Immunol . 2010 Dec; 127(1):254-61, 261.e1-6. PMID: 21126757
Background: Asthma is a major public health burden worldwide. Studies from our group and others have demonstrated that SERPINB3 and SERPINB4 are induced in patients with asthma; however, their mechanistic...
23.
Sivaprasad U, Warrier M, Gibson A, Chen W, Tabata Y, Bass S, et al.
J Immunol . 2010 Oct; 185(11):6802-8. PMID: 20971924
IL-13 is expressed in lesions of atopic dermatitis (AD) and has been associated with increased disease severity. IL-13 has two cognate receptors: IL-13Rα1 and IL-13Rα2. Although IL-13Rα2 expression is known...
24.
Chen W, Sivaprasad U, Tabata Y, Gibson A, Stier M, Finkelman F, et al.
J Immunol . 2009 Dec; 183(12):7870-6. PMID: 20007572
Although mice have nanogram per milliliter serum levels of soluble (s) IL-13Ralpha2, humans lack sIL-13Ralpha2 in serum. Our data provide a mechanism for this biological divergence. In mice, discrete transcripts...
25.
Chen W, Tabata Y, Gibson A, Daines M, Warrier M, Wills-Karp M, et al.
J Allergy Clin Immunol . 2008 Aug; 122(3):625-32. PMID: 18694590
Background: IL-13 receptor alpha2 (IL-13R alpha 2) is a high-affinity receptor for IL-13, a central mediator of allergic asthma. It acts predominantly as a decoy receptor but can also contribute...
26.
Daines M, Chen W, Tabata Y, Walker B, Gibson A, Masino J, et al.
J Allergy Clin Immunol . 2006 Dec; 119(2):375-83. PMID: 17140645
Background: Allergic sensitization affects half of western populations and often precedes the development of allergic disorders including asthma. Despite the critical role of allergens in the pathogenesis of these disorders,...
27.
Tabata Y, Chen W, Warrier M, Gibson A, Daines M, Khurana Hershey G
J Immunol . 2006 Nov; 177(11):7905-12. PMID: 17114462
IL-13 is a key mediator of allergic inflammation. Its diverse functions are mediated by a complex receptor system including IL-4Ralpha, IL-13Ralpha1, and IL-13Ralpha2. IL-4Ralpha and IL-13Ralpha1 form a high-affinity signaling...