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Aaron M Gibson

Explore the profile of Aaron M Gibson including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 808
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Recent Articles
11.
Zhang Z, Xiao C, Gibson A, Bass S, Khurana Hershey G
J Immunol . 2013 Dec; 192(3):859-66. PMID: 24337738
Despite the important role for epidermal growth factor (EGF) in epithelial homeostasis and wound healing, it has not been investigated in atopic dermatitis (AD). We used AD animal models to...
12.
Brandt E, Kovacic M, Lee G, Gibson A, Acciani T, Le Cras T, et al.
J Allergy Clin Immunol . 2013 Sep; 132(5):1194-1204.e2. PMID: 24060272
Background: IL-17A has been implicated in severe forms of asthma. However, the factors that promote IL-17A production during the pathogenesis of severe asthma remain undefined. Diesel exhaust particles (DEPs) are...
13.
Brandt E, Gibson A, Bass S, Rydyznski C, Khurana Hershey G
J Immunol . 2013 Sep; 191(7):3519-25. PMID: 23997219
Despite its presence on resident skin cells, the role of TLR4 in skin diseases remains poorly understood. This is highly significant because the skin biome is rich with potential TLR4...
14.
Chen W, Sivaprasad U, Gibson A, Ericksen M, Cunningham C, Bass S, et al.
J Allergy Clin Immunol . 2013 Jun; 132(4):951-8.e1-6. PMID: 23763980
Background: IL-13 receptor α2 (IL-13Rα2) binds IL-13 with high affinity and modulates IL-13 responses. There are soluble and membrane forms of IL-13Rα2 generated by alternative splicing in mice, but human...
15.
Lee G, Brandt E, Xiao C, Gibson A, Le Cras T, Brown L, et al.
PLoS One . 2013 Apr; 8(3):e60632. PMID: 23555996
Background: Diesel exhaust particle (DEP) exposure enhances allergic inflammation and has been linked to the incidence of asthma. Oxidative stress on the thiol molecules cysteine (Cys) and glutathione (GSH) can...
16.
Mintz-Cole R, Brandt E, Bass S, Gibson A, Reponen T, Khurana Hershey G
J Allergy Clin Immunol . 2013 Feb; 132(1):159-69. PMID: 23403046
Background: It is well accepted that mold exposure is a major contributor to the development of asthma, and beta-glucans are often used as a surrogate for mold exposure in the...
17.
Mintz-Cole R, Gibson A, Bass S, Budelsky A, Reponen T, Khurana Hershey G
J Immunol . 2012 Sep; 189(7):3609-17. PMID: 22962686
There is considerable evidence supporting a role for mold exposure in the pathogenesis and expression of childhood asthma. Aspergillus versicolor and Cladosporium cladosporioides are common molds that have been implicated...
18.
Martin L, Gupta J, Jyothula S, Kovacic M, Biagini Myers J, Patterson T, et al.
PLoS One . 2012 Apr; 7(4):e33454. PMID: 22536318
Rationale And Objective: Autophagy is a cellular process directed at eliminating or recycling cellular proteins. Recently, the autophagy pathway has been implicated in immune dysfunction, the pathogenesis of inflammatory disorders,...
19.
Kovacic M, Biagini Myers J, Wang N, Martin L, Lindsey M, Ericksen M, et al.
PLoS One . 2011 Sep; 6(8):e23714. PMID: 21912604
Background: Asthma is a chronic inflammatory disease with a strong genetic predisposition. A major challenge for candidate gene association studies in asthma is the selection of biologically relevant genes. Methodology/principal...
20.
Schroer K, Gibson A, Sivaprasad U, Bass S, Ericksen M, Wills-Karp M, et al.
J Allergy Clin Immunol . 2011 May; 128(3):539-48. PMID: 21570714
Background: Glutathione S-transferase pi (GSTPi) is the predominant redox regulator in the lung. Although evidence implicates an important role for GSTPi in asthma, the mechanism for this has remained elusive....