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Umasundari Sivaprasad

Explore the profile of Umasundari Sivaprasad including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 1468
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Recent Articles
1.
Heymann P, Nguyen H, Steinke J, Turner R, Woodfolk J, Platts-Mills T, et al.
PLoS One . 2017 May; 12(5):e0178096. PMID: 28552993
Background: Rhinovirus (HRV) is associated with the large majority of virus-induced asthma exacerbations in children and young adults, but the mechanisms remain poorly defined. Methods: Asthmatics and non-asthmatic controls were...
2.
Hall S, Baker T, Lajoie S, Richgels P, Yang Y, McAlees J, et al.
J Allergy Clin Immunol . 2016 Jul; 139(2):462-471.e14. PMID: 27417023
Background: Increased IL-17A production has been associated with more severe asthma; however, the mechanisms whereby IL-17A can contribute to IL-13-driven pathology in asthmatic patients remain unclear. Objective: We sought to...
3.
Ghosh D, Ding L, Sivaprasad U, Geh E, Biagini Myers J, Bernstein J, et al.
PLoS One . 2015 Dec; 10(12):e0144316. PMID: 26717000
Several studies have identified genes that are differentially expressed in atopic dermatitis (AD) compared to normal skin. However, there is also considerable variation in the list of differentially expressed genes...
4.
Mersha T, Martin L, Biagini Myers J, Kovacic M, He H, Lindsey M, et al.
Genomics . 2015 Mar; 106(1):15-22. PMID: 25817197
Asthma comprised of highly heterogeneous subphenotypes resulting from complex interplay between genetic and environmental stimuli. While much focus has been placed on extrinsic environmental stimuli, intrinsic environment such as sex...
5.
Sauter S, Wells S, Zhang X, Hoskins E, Davies S, Myers K, et al.
Cancer Epidemiol Biomarkers Prev . 2015 Mar; 24(5):864-72. PMID: 25809863
Background: Fanconi anemia is a rare genetic disorder resulting in a loss of function of the Fanconi anemia-related DNA repair pathway. Individuals with Fanconi anemia are predisposed to some cancers,...
6.
Brandt E, Biagini Myers J, Acciani T, Ryan P, Sivaprasad U, Ruff B, et al.
J Allergy Clin Immunol . 2015 Mar; 136(2):295-303.e7. PMID: 25748065
Background: Exposure to traffic pollution particulate matter, predominantly diesel exhaust particles (DEPs), increases the risk of asthma and asthma exacerbation; however, the underlying mechanisms remain poorly understood. Objective: We sought...
7.
Sivaprasad U, Kinker K, Ericksen M, Lindsey M, Gibson A, Bass S, et al.
J Invest Dermatol . 2014 Aug; 135(1):160-169. PMID: 25111616
Serine proteases are critical for epidermal barrier homeostasis, and their aberrant expression and/or activity is associated with chronic skin diseases. Elevated levels of the serine protease inhibitors SERPINB3 and SERPINB4...
8.
Chen W, Sivaprasad U, Gibson A, Ericksen M, Cunningham C, Bass S, et al.
J Allergy Clin Immunol . 2013 Jun; 132(4):951-8.e1-6. PMID: 23763980
Background: IL-13 receptor α2 (IL-13Rα2) binds IL-13 with high affinity and modulates IL-13 responses. There are soluble and membrane forms of IL-13Rα2 generated by alternative splicing in mice, but human...
9.
Wills-Karp M, Rani R, Dienger K, Lewkowich I, Fox J, Perkins C, et al.
J Exp Med . 2012 Feb; 209(3):607-22. PMID: 22329990
The molecular mechanisms that drive mucosal T helper type 2 (T(H)2) responses against parasitic helminths and allergens remain unclear. In this study, we demonstrate in mice that TFF2 (trefoil factor...
10.
Brandt E, Sivaprasad U
J Clin Cell Immunol . 2011 Oct; 2(3). PMID: 21994899
Atopic dermatitis (AD), a chronic relapsing inflammatory skin disease, is increasing in prevalence around the world. Intensive research is ongoing to understand the mechanisms involved in the development of AD...