Aaron Darling
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Explore the profile of Aaron Darling including associated specialties, affiliations and a list of published articles.
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22
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10983
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Recent Articles
1.
Macaulay M, Darling A, Fourment M
PLoS Comput Biol
. 2023 Apr;
19(4):e1011084.
PMID: 37099595
Bayesian inference for phylogenetics is a gold standard for computing distributions of phylogenies. However, Bayesian phylogenetics faces the challenging computational problem of moving throughout the high-dimensional space of trees. Fortunately,...
2.
Yasir M, Turner A, Bastkowski S, Baker D, Page A, Telatin A, et al.
Genome Res
. 2020 Feb;
30(2):239-249.
PMID: 32051187
Understanding the genetic basis for a phenotype is a central goal in biological research. Much has been learnt about bacterial genomes by creating large mutant libraries and looking for conditionally...
3.
Cooke I, Mead O, Whalen C, Boote C, Moya A, Ying H, et al.
Zoology (Jena)
. 2019 Nov;
137:125695.
PMID: 31759226
It is now recognised that the biology of almost any organism cannot be fully understood without recognising the existence and potential functional importance of associated microbes. Arguably, the emergence of...
4.
Van Deynze A, Zamora P, Delaux P, Heitmann C, Jayaraman D, Rajasekar S, et al.
PLoS Biol
. 2018 Aug;
16(8):e2006352.
PMID: 30086128
Plants are associated with a complex microbiota that contributes to nutrient acquisition, plant growth, and plant defense. Nitrogen-fixing microbial associations are efficient and well characterized in legumes but are limited...
5.
Gardiner M, Vicaretti M, Sparks J, Bansal S, Bush S, Liu M, et al.
PeerJ
. 2017 Jul;
5:e3543.
PMID: 28740749
Background: Type II diabetes is a chronic health condition which is associated with skin conditions including chronic foot ulcers and an increased incidence of skin infections. The skin microbiome is...
6.
Liu M, Darling A
F1000Res
. 2016 Mar;
4:1377.
PMID: 27006753
We review currently available technologies for deconvoluting metagenomic data into individual genomes that represent populations, strains, or genotypes present in the community. An evaluation of chromosome conformation capture (3C) and...
7.
Pineda S, Sollod B, Wilson D, Darling A, Sunagar K, Undheim E, et al.
BMC Genomics
. 2014 Mar;
15:177.
PMID: 24593665
Background: Spiders have evolved pharmacologically complex venoms that serve to rapidly subdue prey and deter predators. The major toxic factors in most spider venoms are small, disulfide-rich peptides. While there...
8.
Rinke C, Schwientek P, Sczyrba A, Ivanova N, Anderson I, Cheng J, et al.
Nature
. 2013 Jul;
499(7459):431-7.
PMID: 23851394
Genome sequencing enhances our understanding of the biological world by providing blueprints for the evolutionary and functional diversity that shapes the biosphere. However, microbial genomes that are currently available are...
9.
Islam A, Labbate M, Djordjevic S, Alam M, Darling A, Melvold J, et al.
Open Biol
. 2013 Feb;
3(2):120181.
PMID: 23407641
Of the 200+ serogroups of Vibrio cholerae, only O1 or O139 strains are reported to cause cholera, and mostly in endemic regions. Cholera outbreaks elsewhere are considered to be via...
10.
Rands C, Darling A, Fujita M, Kong L, Webster M, Clabaut C, et al.
BMC Genomics
. 2013 Feb;
14:95.
PMID: 23402223
Background: A classical example of repeated speciation coupled with ecological diversification is the evolution of 14 closely related species of Darwin's (Galápagos) finches (Thraupidae, Passeriformes). Their adaptive radiation in the...