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Aaron Carmody

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Articles 21
Citations 371
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Recent Articles
1.
Port J, Riopelle J, Smith S, Myers L, Kaiser F, Lewis M, et al.
Nat Microbiol . 2024 Apr; 9(5):1231-1243. PMID: 38649413
The 2022 mpox virus (MPXV) outbreak was sustained by human-to-human transmission; however, it is currently unclear which factors lead to sustained transmission of MPXV. Here we present Mastomys natalensis as...
2.
van Tol S, Fletcher P, Feldmann F, Mukesh R, Port J, Gallogly S, et al.
J Infect Dis . 2024 Mar; 230(5):1083-1092. PMID: 38487996
The most recent Sudan virus (SUDV) outbreak in Uganda was first detected in September 2022 and resulted in 164 laboratory-confirmed cases and 77 deaths. There are no approved vaccines against...
3.
Rao D, Meade-White K, Leventhal S, Mihalakakos E, Carmody A, Feldmann H, et al.
EBioMedicine . 2023 Oct; 97:104839. PMID: 37866114
Background: Crimean-Congo haemorrhagic fever (CCHF) is a serious viral hemorrhagic fever caused by the CCHF virus (CCHFV). Spread by the bites of infected ticks or handling of viremic livestock, human...
4.
Dimond Z, Bauler L, Zhang Y, Carmody A, Hackstadt T
mSphere . 2022 Oct; 7(6):e0042322. PMID: 36286535
Mitochondria are critical cellular organelles that perform a wide variety of functions, including energy production and immune regulation. To perform these functions, mitochondria contain approximately 1,500 proteins, the majority of...
5.
Roberts L, Anderson R, Carmody A, Bosio C
Appl Biosaf . 2022 Aug; 26(4):205-209. PMID: 36034097
Fluorescent-activated cell sorting (FACS) is often the most appropriate technique to obtain pure populations of a cell type of interest for downstream analysis. However, aerosol droplets can be generated during...
6.
Speranza E, Purushotham J, Port J, Schwarz B, Flagg M, Williamson B, et al.
Life Sci Alliance . 2022 Jan; 5(4). PMID: 35039442
Advanced age is a key predictor of severe COVID-19. To gain insight into this relationship, we used the rhesus macaque model of SARS-CoV-2 infection. Eight older and eight younger macaques...
7.
Rao D, ODonnell K, Carmody A, Weissman I, Hasenkrug K, Marzi A
Antiviral Res . 2021 Dec; 197:105226. PMID: 34923028
It has been shown that a very early cell-intrinsic response to infection is the upregulation of CD47 cell surface expression, a molecule known for delivering a "don't eat me signal"...
8.
van Doremalen N, Purushotham J, Schulz J, Holbrook M, Bushmaker T, Carmody A, et al.
Sci Transl Med . 2021 Jul; 13(607). PMID: 34315826
ChAdOx1 nCoV-19/AZD1222 is an approved adenovirus-based vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being deployed globally. Previous studies in rhesus macaques revealed that intramuscular vaccination with ChAdOx1...
9.
Hasenkrug K, Feldmann F, Myers L, Santiago M, Guo K, Barrett B, et al.
mBio . 2021 Jul; 12(4):e0150321. PMID: 34311582
Severe coronavirus disease 2019 (COVID-19) has been associated with T cell lymphopenia, but no causal effect of T cell deficiency on disease severity has been established. To investigate the specific...
10.
Mlera L, Offerdahl D, Dorward D, Carmody A, Chiramel A, Best S, et al.
Emerg Microbes Infect . 2021 Jun; 10(1):1378-1389. PMID: 34162308
The vector-borne flaviviruses (VBFVs) are well known for causing great misery and death in humans worldwide. The VBFVs include those transmitted by mosquitos, such as Zika virus (ZIKV), dengue virus;...