Aaron Babendreyer
Overview
Explore the profile of Aaron Babendreyer including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
273
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0
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Recent Articles
1.
Sester S, Wilms G, Ahlburg J, Babendreyer A, Becker W
BMC Cancer
. 2024 Nov;
24(1):1341.
PMID: 39482615
Background: The protein kinase DYRK1B is a negative regulator of cell proliferation but has been found to be overexpressed in diverse human solid cancers. While DYRK1B is recognized to promote...
2.
Vorwerk V, Wilms G, Babendreyer A, Becker W
Sci Rep
. 2024 Oct;
14(1):23926.
PMID: 39397076
The protein kinases DYRK1A and DYRK1B are pivotal regulators of cell cycle progression by promoting cell cycle exit into quiescence. DYRK1B appears to play a more important role in cancer...
3.
Wilms G, Schofield K, Maddern S, Foley C, Shaw Y, Smith B, et al.
J Med Chem
. 2024 Sep;
67(19):17259-17289.
PMID: 39344427
Small-molecule-induced protein degradation has emerged as a promising pharmacological modality for inactivating disease-relevant protein kinases. DYRK1A and DYRK1B are closely related protein kinases that are involved in pathological processes such...
4.
Babendreyer A, Kieselhorst J, Rinkens C, Lyashenko A, Dusterhoft S, Jahr H, et al.
Cell Commun Signal
. 2024 Jun;
22(1):322.
PMID: 38863060
Bone resorption is driven through osteoclast differentiation by macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor kappa-Β ligand (RANKL). We noted that a disintegrin and metalloproteinase (ADAM) 10...
5.
Blasius K, Ludwig L, Knapp S, Flasshove C, Sonnabend F, Keller D, et al.
Cell Mol Life Sci
. 2024 Feb;
81(1):102.
PMID: 38409522
The protease ADAM17 plays an important role in inflammation and cancer and is regulated by iRhom2. Mutations in the cytosolic N-terminus of human iRhom2 cause tylosis with oesophageal cancer (TOC)....
6.
Dreschers S, Platen C, Oppermann L, Doughty C, Ludwig A, Babendreyer A, et al.
J Immunol Res
. 2023 Dec;
2023:8883045.
PMID: 38046264
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR) and has been shown to regulate the phagocytosis-induced cell death of monocytes in peripheral blood. AREG-dependent apoptotic signaling...
7.
Rojas-Gonzalez D, Babendreyer A, Ludwig A, Mela P
Sci Rep
. 2023 Sep;
13(1):14384.
PMID: 37658092
Endothelialization of tissue-engineered vascular grafts has proven crucial for implant functionality and thus clinical outcome, however, the choice of endothelial cells (ECs) is often driven by availability rather than by...
8.
Grannemann C, Pabst A, Honert A, Schieren J, Martin C, Hank S, et al.
Biomater Adv
. 2023 Jun;
152:213516.
PMID: 37348330
In the lung, pulmonary epithelial cells undergo mechanical stretching during ventilation. The associated cellular mechanoresponse is still poorly understood at the molecular level. Here, we demonstrate that activation of the...
9.
Kahveci-Turkoz S, Blasius K, Wozniak J, Rinkens C, Seifert A, Kasparek P, et al.
Cell Mol Life Sci
. 2023 Apr;
80(5):135.
PMID: 37119365
Several membrane-anchored signal mediators such as cytokines (e.g. TNFα) and growth factors are proteolytically shed from the cell surface by the metalloproteinase ADAM17, which, thus, has an essential role in...
10.
Cheremkhina M, Klein S, Babendreyer A, Ludwig A, Schmitz-Rode T, Jockenhoevel S, et al.
Micromachines (Basel)
. 2023 Mar;
14(3).
PMID: 36984982
The endothelialization of gas exchange membranes can increase the hemocompatibility of extracorporeal membrane oxygenators and thus become a long-term lung replacement option. Cell seeding on large or uneven surfaces of...