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Daniela Dreymueller

Explore the profile of Daniela Dreymueller including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 727
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Recent Articles
1.
Babendreyer A, Molls L, Simons I, Dreymueller D, Biller K, Jahr H, et al.
J Mol Cell Cardiol . 2019 Jul; 134:51-61. PMID: 31271758
Reduced shear stress resulting from disturbed blood flow can impair endothelial integrity and drive the development of vascular inflammatory lesions. Metalloproteinases of the ADAM family have been implicated in the...
2.
Schick D, Babendreyer A, Wozniak J, Awan T, Noels H, Liehn E, et al.
Atherosclerosis . 2019 Mar; 286:163-171. PMID: 30910225
Background And Aims: Members of the family of a disintegrin and metalloproteinases (ADAMs) and their substrates have been previously shown to modulate the inflammatory response in cardiac diseases, but studies...
3.
Habib P, Dreymueller D, Rosing B, Botung H, Slowik A, Zendedel A, et al.
J Steroid Biochem Mol Biol . 2018 Feb; 178:340-347. PMID: 29448043
Estrogens modulate the immune system and possess anti-inflammatory properties. In line, immune cells express a variety of estrogen receptors (ER) including ER-alpha and -beta. In the present study, we examined...
4.
Ruther B, Scheld M, Dreymueller D, Clarner T, Kress E, Brandenburg L, et al.
Glia . 2017 Aug; 65(12):1900-1913. PMID: 28836302
Brain-intrinsic degenerative cascades are a proposed factor driving inflammatory lesion formation in multiple sclerosis (MS) patients. We recently described a model combining noninflammatory cytodegeneration (via cuprizone) with the classic active...
5.
Dreymueller D, Pruessmeyer J, Schumacher J, Fellendorf S, Hess F, Seifert A, et al.
Am J Physiol Lung Cell Mol Physiol . 2017 Jun; 313(3):L602-L614. PMID: 28596294
Alveolar leukocyte recruitment is a hallmark of acute lung inflammation and involves transmigration of leukocytes through endothelial and epithelial layers. The disintegrin and metalloproteinase (ADAM) 8 is expressed on human...
6.
Babendreyer A, Molls L, Dreymueller D, Uhlig S, Ludwig A
Mediators Inflamm . 2017 May; 2017:1515389. PMID: 28522896
Flow conditions critically regulate endothelial cell functions in the vasculature. Reduced shear stress resulting from disturbed blood flow can drive the development of vascular inflammatory lesions. On endothelial cells, the...
7.
Koenen A, Babendreyer A, Schumacher J, Pasqualon T, Schwarz N, Seifert A, et al.
PLoS One . 2017 Mar; 12(3):e0173486. PMID: 28267793
The CXC-chemokine receptor 6 (CXCR6) is a class A GTP-binding protein-coupled receptor (GPCRs) that mediates adhesion of leukocytes by interacting with the transmembrane cell surface-expressed chemokine ligand 16 (CXCL16), and...
8.
Groth E, Pruessmeyer J, Babendreyer A, Schumacher J, Pasqualon T, Dreymueller D, et al.
Biochim Biophys Acta . 2016 Sep; 1863(11):2795-2808. PMID: 27599715
By mediating proteolytic shedding on the cell surface the disintegrin and metalloproteinases ADAM10 and ADAM17 function as critical regulators of growth factors, cytokines and adhesion molecules. We here report that...
9.
Dreymueller D, Ludwig A
Platelets . 2016 Jul; 28(4):354-361. PMID: 27460023
Proteases of the disintegrin and metalloproteinase (ADAM) family mediate the proteolytic shedding of various surface molecules including cytokine precursors, adhesion molecules, growth factors, and receptors. Within the vasculature ADAM10 and...
10.
Kuhn P, Colombo A, Schusser B, Dreymueller D, Wetzel S, Schepers U, et al.
Elife . 2016 Jan; 5. PMID: 26802628
Metzincin metalloproteases have major roles in intercellular communication by modulating the function of membrane proteins. One of the proteases is the a-disintegrin-and-metalloprotease 10 (ADAM10) which acts as alpha-secretase of the...