A Reifel-Miller
Overview
Explore the profile of A Reifel-Miller including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
46
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0
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Recent Articles
1.
Gernert D, Neel D, Boehm M, Leibowitz M, Mais D, Michellys P, et al.
Bioorg Med Chem Lett
. 2004 May;
14(11):2759-63.
PMID: 15125928
Benzofused heterocyclic analogs of the RXR selective modulator 1 (LG101506) were synthesized, and tested for their ability to bind RXRalpha and activate RXR homo and heterodimers. Potency and efficacy were...
2.
Gernert D, Ajamie R, Ardecky R, Bell M, Leibowitz M, Mais D, et al.
Bioorg Med Chem Lett
. 2003 Sep;
13(19):3191-5.
PMID: 12951091
Fluorinated trienoic acid analogues of the RXR selective modulator 1 (LG101506) were synthesized, and tested for their ability to bind RXRalpha and activate RXR homo and heterodimers. Potency and efficacy...
3.
Michellys P, Ardecky R, Chen J, Crombie D, Etgen G, Faul M, et al.
J Med Chem
. 2003 Jun;
46(13):2683-96.
PMID: 12801232
Previous data have shown that RXR-selective agonists (e.g., 3 and 4) are insulin sensitizers in rodent models of non-insulin-dependent diabetes mellitus (NIDDM). Unfortunately, they also produce dramatic increases in triglycerides...
4.
Del Zotto H, Massa L, Rafaeloff R, Pittenger G, Vinik A, Gold G, et al.
J Endocrinol
. 2000 Jun;
165(3):725-33.
PMID: 10828857
The possible relationship between changes in islet cell mass and in islet neogenesis-associated protein (INGAP)-cell mass induced by sucrose administration to normal hamsters was investigated. Normal hamsters were given sucrose...
5.
Cousin S, Hugl S, Myers Jr M, White M, Reifel-Miller A, Rhodes C
Biochem J
. 1999 Dec;
344 Pt 3:649-58.
PMID: 10585851
Mitogenic signal-transduction pathways have not been well defined in pancreatic beta-cells. In the glucose-sensitive rat beta-cell line, INS-1, glucose (6-18 mM) increased INS-1 cell proliferation (>20-fold at 15 mM glucose)....
6.
Birch K, Heath W, Hermeling R, Johnston C, Stramm L, Dell C, et al.
Diabetes
. 1996 May;
45(5):642-50.
PMID: 8621017
Previous studies have shown that high glucose levels and diabetes induce an elevation in protein kinase C (PKC) activity in vascular cells and tissues susceptible to diabetic complications. In addition,...
7.
Derigs H, Reifel-Miller A, Kaushansky K, Hromas R, Boswell H
Exp Hematol
. 1994 Aug;
22(9):924-32.
PMID: 8062890
We have reported modulation, by cytokines interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) and by hormonal cyclic-adenosine-monophosphate (cAMP) agonists, of hematopoietic growth factor production in the murine marrow...
8.
Stewart M, Cox G, Reifel-Miller A, Kim S, Westbrook C, Leibowitz D
J Biol Chem
. 1994 Apr;
269(14):10820-9.
PMID: 8144670
A reciprocal translocation between chromosomes 9 and 22 creates the Philadelphia (Ph1) chromosome in chronic myelogenous leukemia. This translocation results in the fusion of the ABL and the BCR genes...