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A R Dahl

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Articles 90
Citations 366
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Recent Articles
1.
Gerde P, Muggenburg B, Lundborg M, Tesfaigzi Y, Dahl A
Res Rep Health Eff Inst . 2001 Aug; (101):5-25; discussion 27-32. PMID: 11488545
Exposure to diesel exhaust is a suspected risk factor for human lung cancer. The carbonaceous core of the soot particles found in diesel exhaust and the condensed organic compounds adsorbed...
2.
Gerde P, Muggenburg B, Lundborg M, Dahl A
Carcinogenesis . 2001 Apr; 22(5):741-9. PMID: 11323393
Exposure to diesel exhaust may contribute to lung cancer in humans. It remains unclear whether the carbonaceous core of the soot particle or its coat of adsorbed/condensed organics contributes most...
3.
Henderson R, Bechtold W, Dahl A
Toxicology . 2001 Mar; 160(1-3):81-6. PMID: 11246127
The carcinogenicity of 1,3-butadiene (BD) varies greatly in the rodent species in which 2-year bioassay studies were completed. This raises the question of whether the risk of BD exposure in...
4.
Wang D, Marko M, Dahl A, Engelke K, Placke M, Imondi A, et al.
Clin Cancer Res . 2000 Sep; 6(9):3636-45. PMID: 10999756
Chemopreventive retinoids may be more effective if delivered to the lung epithelium by inhalation. 13-cis-Retinoic acid (13-cis-RA) was comparable to all-trans-retinoic acid (RA) in inducing transglutaminase II (TGase II) in...
5.
Dahl A, Grossi I, Houchens D, Scovell L, Placke M, Imondi A, et al.
Clin Cancer Res . 2000 Aug; 6(8):3015-24. PMID: 10955779
In previously treated head-and-neck cancer patients, p.o. administered isotretinoin (13-cis retinoic acid) reduced the occurrence of second aerodigestive tumors, including lung tumors, but side effects made chronic therapy problematic. We...
6.
Dahl A, Henderson R
Inhal Toxicol . 2000 Jul; 12(5):439-51. PMID: 10880138
The chronic (2-yr) inhalation toxicity of 1,3-butadiene (BD), a chemical used in large quantities to make rubber and plastics, differs greatly between mice and rats. Mice develop lung tumors after...
7.
Henderson R, Hahn F, Benson J, Barr E, Bechtold W, Burt D, et al.
Toxicol Sci . 1999 Sep; 51(1):146-52. PMID: 10496686
Butadiene diepoxide (BDO2), a metabolite of 1,3-butadiene (BD) and potent mutagen, is suspected to be a proximate carcinogen in the multisite tumorigenesis in B6C3F1 mice exposed to BD. Rats, in...
8.
Dahl A, Allen M, Bechtold W, Griffith Jr W, Henderson R
Toxicol Sci . 1998 May; 41(2):167-73. PMID: 9520352
1,3-Butadiene (BD), a compound used extensively in the rubber industry, is weakly carcinogenic in Sprague-Dawley rats after chronic exposures to concentrations of 1000 and 8000 ppm. Conversely, in B6C3F1 mice,...
9.
Wardlaw S, Nikula K, Kracko D, Finch G, Dahl A
Carcinogenesis . 1998 May; 19(4):655-62. PMID: 9600351
Enzymes of the nasal tissue, one of the first tissues to contact inhaled toxicants, are relatively resistant to induction by traditional inducers. Because tobacco smoke has been shown to induce...
10.
Gerde P, Muggenburg B, Stephens T, Lewis J, Pyon K, Dahl A
Cancer Res . 1998 Apr; 58(7):1417-22. PMID: 9537242
Lung cancer is largely a site-of-entry disease caused by inhaled carcinogenic agents, especially tobacco smoke. Two major groups of procarcinogens, tobacco-specific nitrosamines and polycyclic aromatic hydrocarbons, are putative agents, but...