A L Sieron
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Explore the profile of A L Sieron including associated specialties, affiliations and a list of published articles.
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25
Citations
428
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Recent Articles
1.
Schumann H, Kiritsi D, Pigors M, Hausser I, Kohlhase J, Peters J, et al.
Br J Dermatol
. 2013 Mar;
169(1):115-24.
PMID: 23496044
Background: Integrin α6β4 is a transmembrane receptor and a key component of the hemidesmosome anchoring complex. It is involved in cell-matrix adhesion and signalling in various tissues. Mutations in the...
2.
Fertala A, Sieron A, Adachi E, Jimenez S
Biochemistry
. 2001 Nov;
40(48):14422-8.
PMID: 11724554
Single amino acid substitutions in collagen II cause heterogeneous cartilage disorders including some chondrodysplasias and certain forms of heritable osteoarthritis. In this study, we examined molecular interactions between normal collagen...
3.
Kramerova I, Kawaguchi N, Fessler L, Nelson R, Chen Y, Kramerov A, et al.
Development
. 2000 Nov;
127(24):5475-85.
PMID: 11076767
Papilin is an extracellular matrix glycoprotein that we have found to be involved in, (1) thin matrix layers during gastrulation, (2) matrix associated with wandering, phagocytic hemocytes, (3) basement membranes...
4.
Sieron A, Tretiakova A, Jameson B, SEGALL M, Lund-Katz S, Khan M, et al.
Biochemistry
. 2000 Mar;
39(12):3231-9.
PMID: 10727214
Procollagen C-proteinase-2 (pCP-2, mTld) is derived from the longest splicing variant of the gene encoding bone morphogenetic protein 1 (BMP-1). The variants have identical amino terminal signal peptides, prodomains and...
5.
Colige A, Sieron A, Li S, Schwarze U, Petty E, Wertelecki W, et al.
Am J Hum Genet
. 1999 Jul;
65(2):308-17.
PMID: 10417273
Ehlers-Danlos syndrome (EDS) type VIIC is a recessively inherited connective-tissue disorder, characterized by extreme skin fragility, characteristic facies, joint laxity, droopy skin, umbilical hernia, and blue sclera. Like the animal...
6.
Arnold W, Fertala A, Sieron A, Hattori H, Mechling D, Bachinger H, et al.
J Biol Chem
. 1998 Nov;
273(48):31822-8.
PMID: 9822649
A cDNA cassette system was used to synthesize recombinant versions of procollagen II in which one of the four blocks of 234 amino acids that define a repeating D periods...
7.
Krynska B, Lewin-Kowalik J, Sieron A
Postepy Hig Med Dosw
. 1998 Oct;
52(3):237-57.
PMID: 9789434
The mechanism that may lead to tumor formation in SV40 or JCV infected tissues based on previously reported interactions between T antigens and two factors (p53 and pRb) controlling cell...
8.
Prockop D, Sieron A, Li S
Matrix Biol
. 1998 Apr;
16(7):399-408.
PMID: 9524360
As soon as procollagen precursors of fibrillar collagens were discovered in the early 1970s, it became apparent that connective tissues must contain proteolytic activities that cleave the N-propeptides and the...
9.
Zafarullah K, Sieron A, Fertala A, Tromp G, Kuivaniemi H, Prockop D
Matrix Biol
. 1998 Mar;
16(5):245-53.
PMID: 9501325
A D-period cassette system was developed that can be used to synthesize a variety of recombinant homotrimers of type I procollagen. A construct lacking the central two D-periods of pro...
10.
Zafarullah K, Brown E, Kuivaniemi H, Tromp G, Sieron A, Fertala A, et al.
Matrix Biol
. 1997 Dec;
16(4):201-9.
PMID: 9402010
A cDNA was prepared that coded for the signal peptide of type III procollagen linked to the complete C-propeptide of the protein. The cDNA was then used to express the...