D J Prockop
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Explore the profile of D J Prockop including associated specialties, affiliations and a list of published articles.
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456
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Recent Articles
1.
Ullah M, Kuroda Y, Bartosh T, Liu F, Zhao Q, Gregory C, et al.
Cell Death Discov
. 2017 Aug;
3:17029.
PMID: 28845293
[This corrects the article DOI: 10.1038/cddiscovery.2016.64.].
2.
Ullah M, Kuroda Y, Bartosh T, Liu F, Zhao Q, Gregory C, et al.
Cell Death Discov
. 2017 Feb;
3:16064.
PMID: 28179988
One attractive strategy to treat cancers is to deliver an exogenous enzyme that will convert a non-toxic compound to a highly toxic derivative. The strategy was tested with viral vectors...
3.
Horie M, Choi H, Lee R, Reger R, Ylostalo J, Muneta T, et al.
Osteoarthritis Cartilage
. 2012 Jul;
20(10):1197-207.
PMID: 22750747
Objective: Meniscal regeneration was previously shown to be enhanced by injection of mesenchymal stem/stromal cells (MSCs) but the mode of action of the MSCs was not established. The aim of...
4.
Scheibe F, Gladow N, Mergenthaler P, Tucker A, Meisel A, Prockop D, et al.
Gene Ther
. 2011 Sep;
19(5):550-60.
PMID: 21956691
Erythropoietin (EPO) acts on erythroblasts in the bone marrow (BM) to stimulate the formation of red blood cells. In this study, we wanted to determine whether BM-derived mesenchymal stromal cells...
5.
Lee N, Smolarz A, Olson S, David O, Reiser J, Kutner R, et al.
Br J Cancer
. 2007 Nov;
97(11):1552-9.
PMID: 17987039
Canonical Wnt signalling is an osteoinductive signal that promotes bone repair through acceleration of osteogenic differentiation by progenitors. Dkk-1 is a secreted inhibitor of canonical Wnt signalling and thus inhibits...
6.
Prockop D
Clin Pharmacol Ther
. 2007 Aug;
82(3):241-3.
PMID: 17700588
There has recently been an explosion of interest in adult stem/progenitor cells that have the potential to repair tissues, with over 3,000 citations to publications (PubMed) and numerous announcements of...
7.
Nieminen J, Sahlman J, Hirvonen T, Jamsa T, Tuukkanen J, Kovanen V, et al.
Calcif Tissue Int
. 2005 May;
77(2):104-12.
PMID: 15920676
The objective of this study was to evaluate the influence of heterozygous inactivation of one allele of the type II collagen gene (Col2a1) on biomechanical properties and mineral density of...
8.
Pochampally R, Horwitz E, DiGirolamo C, Stokes D, Prockop D
Gene Ther
. 2005 Apr;
12(14):1119-25.
PMID: 15815702
Gene therapy for dominant-negative disorders presents a more difficult challenge than gene therapy for recessive disorders, since even partial replacement of a protein for a recessive disorder can reverse symptoms....
9.
Peister A, Mellad J, Wang M, Tucker H, Prockop D
Gene Ther
. 2004 Jan;
11(2):224-8.
PMID: 14712307
Human marrow stromal cells (hMSCs) are an attractive source of adult stem cells for autologous cell and gene therapy. To transfect hMSCs without the use of viruses, we developed improved...
10.
Prockop D, Sekiya I, COLTER D
Cytotherapy
. 2002 Apr;
3(5):393-6.
PMID: 11953019
Background: The adult stem cells from BM, known as non-hematopoietic mesenchymal stem cells, or marrow stromal cells (MSCs), readily generate single-cell-derived colonies, but the cultures are known to contain cells...