A L Cozens
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Explore the profile of A L Cozens including associated specialties, affiliations and a list of published articles.
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12
Citations
661
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Recent Articles
1.
Cozens A, Yezzi M, Kunzelmann K, Ohrui T, Chin L, Eng K, et al.
Am J Respir Cell Mol Biol
. 1994 Jan;
10(1):38-47.
PMID: 7507342
A major limitation in the study of vectorial ion transport, secretion, and differentiated function in the human airway epithelium has been the lack of suitable cell culture systems. Progress in...
2.
Cozens A, Yezzi M, Yamaya M, Steiger D, Wagner J, Garber S, et al.
In Vitro Cell Dev Biol
. 1992 Nov;
28A(11-12):735-44.
PMID: 1282914
The successful establishment of a postcrisis SV-40 T antigen transformed epithelial cell line, 1HAEo-, which retains tight junctions and vectorial ion transport, is described. Immunocytochemical analysis of 1HAEo- cells shows...
3.
Cozens A, Yezzi M, Chin L, Simon E, Finkbeiner W, Wagner J, et al.
Proc Natl Acad Sci U S A
. 1992 Jun;
89(11):5171-5.
PMID: 1375758
Tracheobronchial glands were isolated and cultured from a patient with cystic fibrosis (CF). Cultured epithelial cells were transformed with pSVori-. All transformed cell lines express cytokeratin filaments and at early...
4.
Gruenert D, Cozens A
Am J Physiol
. 1991 Jun;
260(6 Pt 1):L386-94.
PMID: 2058684
Inherited phenotypic changes in cultured cells, as observed during differentiation and transformation, reflect alterations in gene expression and have both a genetic and epigenetic basis. The causes of specific changes...
5.
Wagner J, Cozens A, Schulman H, Gruenert D, Stryer L, Gardner P
Nature
. 1991 Feb;
349(6312):793-6.
PMID: 1705665
Cystic fibrosis is associated with defective regulation of apical membrane chloride channels in airway epithelial cells. These channels in normal cells are activated by cyclic AMP-dependent protein kinase and protein...
6.
Cozens A, Yezzi M, Chin L, Simon E, Friend D, Gruenert D
Adv Exp Med Biol
. 1991 Jan;
290:187-94; discussion 194-6.
PMID: 1950742
The inability of beta-adrenergic agonists (eg. isoproterenol) to activate a specific apical membrane chloride channel in epithelial cells is characteristic of cystic fibrosis (CF). The study of these channels has...
7.
Cozens A, Runswick M, Walker J
J Mol Biol
. 1989 Mar;
206(2):261-80.
PMID: 2541251
Mitochondrial ADP/ATP translocase is an abundant component of the inner membrane. It carries ATP from the matrix into the intermembrane space and transports ADP back. Clones coding for two different...
8.
Cozens A, Walker J
Biochem J
. 1988 Jun;
252(2):563-9.
PMID: 2843173
A gene was discovered in the cyanobacterium Synechococcus 6301 that encodes a protein highly related to members of the [2Fe-2S] ferredoxin family found in chloroplasts and cyanobacteria. It follows a...
9.
Cozens A, Walker J
J Mol Biol
. 1987 Apr;
194(3):359-83.
PMID: 3041005
The nucleotide sequence has been determined of two regions of DNA cloned from the cyanobacterium Synechococcus 6301. The larger, 8890 base-pairs in length, contains a cluster of seven genes for...
10.
Walker J, Cozens A, Dyer M, Fearnley I, Powell S, Runswick M
Biochem Soc Trans
. 1987 Feb;
15(1):104-6.
PMID: 3030835
No abstract available.