A K Larsen
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Explore the profile of A K Larsen including associated specialties, affiliations and a list of published articles.
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74
Citations
899
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Recent Articles
1.
Mortensen M, Larsen A, Skadhauge L, Hogsted R, Beermann T, Cook M, et al.
Clin Nutr ESPEN
. 2019 Mar;
30:113-118.
PMID: 30904210
Background/aim: Disease related malnutrition is a major problem in hospitals. Malnutrition in hospitalized patients is caused by many factors. Among these factors are decreased appetite and early satiety, and reaching...
2.
Bleiberg H, Decoster G, de Gramont A, Rougier P, Sobrero A, Benson A, et al.
Ann Oncol
. 2017 Apr;
28(5):922-930.
PMID: 28453700
Background: In respect of the principle of autonomy and the right of self-determination, obtaining an informed consent of potential participants before their inclusion in a study is a fundamental ethical...
3.
Bonnetain F, Borg C, Adams R, Ajani J, Benson A, Bleiberg H, et al.
Ann Oncol
. 2017 Apr;
28(9):2077-2085.
PMID: 28430862
Traditionally, the efficacy of cancer treatment in patients with advance or metastatic disease in clinical studies has been studied using overall survival and more recently tumor-based end points such as...
4.
Akalay I, Tan T, Kumar P, Janji B, Mami-Chouaib F, Charpy C, et al.
Oncogene
. 2014 Jun;
34(17):2261-71.
PMID: 24931170
The molecular basis for the resistance of tumor cells to cell-mediated cytotoxicity remains poorly understood and thus poses a major challenge for cancer immunotherapy. The present study was designed to...
5.
Matuo R, Sousa F, Bonatto D, Mielniczki-Pereira A, Saffi J, Soares D, et al.
Genet Mol Res
. 2013 May;
12(2):1440-56.
PMID: 23661467
Chromatin is thought to modulate access of repair proteins to DNA lesions, and may be altered by chromatin remodelers to facilitate repair. We investigated the participation of chromatin remodelers and...
6.
Selenica M, Jensen H, Larsen A, Pedersen M, Helboe L, Leist M, et al.
Br J Pharmacol
. 2007 Oct;
152(6):959-79.
PMID: 17906685
Background And Purpose: Glycogen synthase kinase-3 (GSK-3) affects neuropathological events associated with Alzheimeŕs disease (AD) such as hyperphosphorylation of the protein, tau. GSK-3beta expression, enzyme activity and tau phosphorylated at...
7.
Larsen A, Brennum L, Egebjerg J, Sanchez C, Halldin C, Andersen P
Br J Pharmacol
. 2004 Mar;
141(6):1015-23.
PMID: 14993096
1. Binding of the novel radioligand (3)H-2-(2-dimethylaminomethyl-phenylsulphanyl)-5-methyl-phenylamine ((3)H-MADAM) to the serotonin transporter (SERT) was used to characterise a range of selective serotonin re-uptake inhibitors (SSRIs) in vitro and in vivo....
8.
Escargueil A, Plisov S, Skladanowski A, Borgne A, Meijer L, Gorbsky G, et al.
FASEB J
. 2001 Aug;
15(12):2288-90.
PMID: 11511510
Although initiation of chromosome condensation during early prophase is linked temporally to the appearance of the mitotic cdc2 kinase in the nucleus, it is not known what targets the kinase...
9.
Larsen A, Gilbert C, Chyzak G, Plisov S, Naguibneva I, Lavergne O, et al.
Cancer Res
. 2001 Apr;
61(7):2961-7.
PMID: 11306474
BN 80915 is the lead compound from a novel class of E-ring modified camptothecin analogues, the homocamptothecins, which show potent antitumor activities in animal models. Here, we report that BN...
10.
Escargueil A, Plisov S, Filhol O, Cochet C, Larsen A
J Biol Chem
. 2000 Aug;
275(44):34710-8.
PMID: 10942766
DNA topoisomerase II alpha is required for chromatin condensation during prophase. This process is temporally linked with the appearance of mitosis-specific phosphorylation sites on topoisomerase IIalpha including one recognized by...