A J Hietaranta
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Explore the profile of A J Hietaranta including associated specialties, affiliations and a list of published articles.
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19
Citations
299
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Recent Articles
1.
Frossard J, Bhagat L, Lee H, Hietaranta A, Singh V, Song A, et al.
Gut
. 2002 Jan;
50(1):78-83.
PMID: 11772971
Background And Aim: Recent studies have indicated that prior thermal stress causes upregulation of heat shock protein 70 (HSP70) expression in the pancreas and protects against secretagogue induced pancreatitis. The...
2.
Singh V, Saluja A, Bhagat L, Hietaranta A, Song A, Mykoniatis A, et al.
Gastroenterology
. 2001 May;
120(7):1818-27.
PMID: 11375962
Background & Aims: The present study was undertaken to evaluate the role of serine proteases in regulating digestive enzyme secretion in pancreatic acinar cells. Methods: Isolated acini were stimulated by...
3.
Hietaranta A, Singh V, Bhagat L, van Acker G, Song A, Mykoniatis A, et al.
J Biol Chem
. 2001 Mar;
276(22):18742-7.
PMID: 11278554
Prior stress ameliorates caerulein-induced pancreatitis in rats. NF-kappaB is a proinflammatory transcription factor activated during caerulein pancreatitis. However, the effects of prior stress on pancreatic NF-kappaB activation are unknown. In...
4.
Hietaranta A, Saluja A, Bhagat L, Singh V, Song A, Steer M
Biochem Biophys Res Commun
. 2001 Feb;
280(1):388-95.
PMID: 11162528
Intra-acinar cell nuclear factor-kappaB (NF-kappaB) and trypsinogen activation are early events in secretagogue-induced acute pancreatitis. We have studied the relationship between NF-kappaB and trypsinogen activation in rat pancreas. CCK analogue...
5.
Halonen K, Leppaniemi A, Puolakkainen P, Lundin J, Kemppainen E, Hietaranta A, et al.
Pancreas
. 2000 Oct;
21(3):266-71.
PMID: 11039471
Acute pancreatitis (AP) is a common abdominal disorder with severity varying from mild to fatal disease. Predicting a patient's outcome remains problematic. The aim of this study was to analyze...
6.
Gao Y, Lecker S, Post M, Hietaranta A, Li J, Volk R, et al.
J Clin Invest
. 2000 Aug;
106(3):439-48.
PMID: 10930447
Induction of NF-kappaB-dependent gene expression plays an important role in a number of biological processes including inflammation and ischemia-reperfusion injury. However, few attempts aimed at selective regulation of this transcription...
7.
Bhagat L, Singh V, Hietaranta A, Agrawal S, Steer M, Saluja A
J Clin Invest
. 2000 Jul;
106(1):81-9.
PMID: 10880051
Rodents given a supramaximally stimulating dose of cholecystokinin or its analogue cerulein develop acute pancreatitis with acinar cell injury, pancreatic inflammation, and intrapancreatic digestive enzyme (i.e., trypsinogen) activation. Prior thermal...
8.
Neoptolemos J, Kemppainen E, Mayer J, Fitzpatrick J, Raraty M, Slavin J, et al.
Lancet
. 2000 Jun;
355(9219):1955-60.
PMID: 10859041
Background: There is a pressing clinical requirement for an early simple test of severity in acute pancreatitis. We investigated the use of an assay of trypsinogen activation peptide (TAP). Methods:...
9.
Nevalainen T, Hietaranta A, Gronroos J
Hepatogastroenterology
. 1999 Nov;
46(29):2731-5.
PMID: 10576338
Phospholipase A2 has been implicated in the pathogenesis and pathophysiology of acute pancreatitis. The initial enthusiasm concerning pancreatic group I phospholipase A2 as an enzyme responsible for pancreatic necrosis and...
10.
Gronroos J, Hietaranta A, Kemppainen E, Nevalainen T
Ann Chir Gynaecol
. 1998 Nov;
87(3):196-9.
PMID: 9825063
No abstract available.