A J El Haj
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Explore the profile of A J El Haj including associated specialties, affiliations and a list of published articles.
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54
Citations
536
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Recent Articles
1.
Dhillon K, Aizel K, Broomhall T, Secret E, Goodman T, Rotherham M, et al.
J R Soc Interface
. 2022 Nov;
19(196):20220576.
PMID: 36349444
A challenge in current stem cell therapies for Parkinson's disease (PD) is controlling neuronal outgrowth from the substantia nigra towards the targeted area where connectivity is required in the striatum....
2.
Monaco G, El Haj A, Alini M, Stoddart M
Eur Cell Mater
. 2021 Jun;
41:616-632.
PMID: 34091884
In vitro models aim to recapitulate the in vivo situation. To more closely mimic the knee joint environment, current in vitro models need improvements to reflect the complexity of the...
3.
Waters S, Schumacher L, El Haj A
NPJ Regen Med
. 2021 Apr;
6(1):24.
PMID: 33846347
Successful progression from bench to bedside for regenerative medicine products is challenging and requires a multidisciplinary approach. What has not yet been fully recognised is the potential for quantitative data...
4.
Yeo E, Markides H, Schade A, Studd A, Oliver J, Waters S, et al.
J R Soc Interface
. 2021 Feb;
18(175):20200558.
PMID: 33593212
A key challenge for stem cell therapies is the delivery of therapeutic cells to the repair site. Magnetic targeting has been proposed as a platform for defining clinical sites of...
5.
Goncalves A, Rotherham M, Markides H, Rodrigues M, Reis R, Gomes M, et al.
Nanomedicine
. 2018 Feb;
14(4):1149-1159.
PMID: 29471171
Stem cell therapies hold potential to stimulate tendon regeneration and homeostasis, which is maintained in response to the native mechanical environment. Activins are members of the mechano-responsive TGF-β superfamily that...
6.
Gillies D, Gamal W, Downes A, Reinwald Y, Yang Y, El Haj A, et al.
Methods
. 2017 Oct;
136:126-133.
PMID: 29080739
Cell mechanical behaviour is increasingly recognised as a central biophysical parameter in cancer and stem cell research, and methods of investigating their mechanical behaviour are therefore needed. We have developed...
7.
Nessler K, Henstock J, El Haj A, Waters S, Whiteley J, Osborne J
J Theor Biol
. 2016 Jan;
394:149-159.
PMID: 26796221
The hydrostatic pressure stimulation of an appropriately cell-seeded porous scaffold within a bioreactor is a promising method for engineering bone tissue external to the body. We propose a mathematical model,...
8.
ODea R, Nelson M, El Haj A, Waters S, Byrne H
Math Med Biol
. 2014 Oct;
32(3):345-66.
PMID: 25323738
In this paper, we consider the derivation of macroscopic equations appropriate to describe the growth of biological tissue, employing a multiple-scale homogenization method to accommodate explicitly the influence of the...
9.
Smith E, Kanczler J, Gothard D, Roberts C, Wells J, White L, et al.
Acta Biomater
. 2014 Jun;
10(10):4186-96.
PMID: 24937137
Current clinical treatments for skeletal conditions resulting in large-scale bone loss include autograft or allograft, both of which have limited effectiveness. In seeking to address bone regeneration, several tissue engineering...
10.
Smith E, Kanczler J, Gothard D, Roberts C, Wells J, White L, et al.
Acta Biomater
. 2014 Jun;
10(10):4197-205.
PMID: 24907660
There is an unmet need for improved, effective tissue engineering strategies to replace or repair bone damaged through disease or injury. Recent research has focused on developing biomaterial scaffolds capable...