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J L Magnay

Explore the profile of J L Magnay including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
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Recent Articles
1.
Whiteley N, Magnay J, McCleary S, Nia S, El Haj A, Rock J
Comp Biochem Physiol A Mol Integr Physiol . 2010 Jun; 157(2):116-22. PMID: 20570748
Recent molecular work has revealed a large diversity of myosin heavy chain (MyHC) gene variants in the abdominal musculature of gammarid amphipods. An unusual truncated MyHC transcript from the loop...
2.
Rock J, Magnay J, Beech S, El Haj A, Goldspink G, Lunt D, et al.
Gene . 2009 Feb; 437(1-2):60-70. PMID: 19236910
To investigate the molecular basis of temperature adaptation in natural populations we used the candidate gene approach, targeting the myosin heavy chain (MyHC) gene. The functional effects of genetic variation...
3.
Magnay J, Holmes J, Neil D, El Haj A
Gene . 2003 Oct; 316:119-26. PMID: 14563558
The temperature- and developmental-regulation of myosin heavy chain (MyHC) expression and primary sequence was investigated in the abdominal musculature of developing Homarus gammarus larvae acclimated to 10, 14 and 19+/-1...
4.
Holmes J, Whiteley N, Magnay J, El Haj A
Comp Biochem Physiol B Biochem Mol Biol . 2002 Apr; 131(3):349-59. PMID: 11959017
The evolutionary adaptations of functional genes to life at low temperatures are not well characterised in marine and fresh water invertebrates. Temperature has been shown to affect the functional characteristics...
5.
Walker L, Preston M, Magnay J, Thomas P, El Haj A
Bone . 2001 Jun; 28(6):603-8. PMID: 11425648
Long-term in vivo studies have highlighted smoking as a risk factor in postmenopausal osteoporosis, bone fracture incidence, and increased nonunion rates. In contrast, there are few data postulating the effects...
6.
Magnay J, Tong J, Drangova R, Baines A
Kidney Int . 2001 Apr; 59(5):1891-8. PMID: 11318961
Background: Oxidized dopamine rapidly forms thiol-conjugates with --SH groups on cysteine, glutathione, and proteins. We used cysteinyl-dopamine production as an index of thioester production during intravenous dopamine treatment of critically...
7.
Peake M, Cooling L, Magnay J, Thomas P, El Haj A
J Appl Physiol (1985) . 2000 Nov; 89(6):2498-507. PMID: 11090608
The regulatory pathways involved in the rapid response of the AP-1 transcription factor, c-fos, to mechanical load in human primary osteoblast-like (HOB) cells and the human MG-63 bone cell line...
8.
Farrell W, Simpson D, Bicknell J, Magnay J, Kyrodimou E, Thakker R, et al.
Br J Cancer . 1999 Jul; 80(1-2):44-50. PMID: 10389976
The majority of pituitary tumours are monoclonal in origin and arise sporadically or occasionally as part of multiple endocrine neoplasia type 1 (MEN1). Whilst a multi-step aetiology involving both oncogenes...
9.
Magnay J, Bayly G
Br J Biomed Sci . 1995 Mar; 52(1):26-30. PMID: 7549603
A 24-hour laboratory-based service was established in the City Hospital, Birmingham, England, in 1987 for semi-quantitative serum human chorionic gonadotrophin (hCG) assay and specific clinical criteria for requests were agreed....