A Ganesan
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Explore the profile of A Ganesan including associated specialties, affiliations and a list of published articles.
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125
Citations
2276
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Recent Articles
11.
Balogun K, Chukwunenye P, Anwar F, Ganesan A, Adesope Q, Willadsen D, et al.
J Chem Phys
. 2022 Sep;
157(10):104701.
PMID: 36109231
Interactions of N at oxide surfaces are important for understanding electrocatalytic nitrogen reduction reaction (NRR) mechanisms. Interactions of N at the polycrystalline vanadium oxide/vapor interface were monitored at room temperature...
12.
Eliandro da Silva Junior P, de Melo S, de Paula M, Vessecchi R, Opatz T, Day J, et al.
Org Biomol Chem
. 2022 Sep;
20(37):7483-7490.
PMID: 36102876
This article discusses the reactivity of 6-azaindazole (1) and 2,6-naphthyridine (2), proposed to be "heteroaromatic rings of the future," which would be useful for fragment-based drug discovery (FBDD) campaigns, developing...
13.
Maujean T, Girard N, Ganesan A, Gulea M, Bonnet D
RSC Adv
. 2022 May;
10(71):43358-43370.
PMID: 35519699
Nitrogen-containing heterocycles represent a major source of pharmacological probes and drug candidates. To extend their molecular diversity and their potential biological activities, it is of importance to design and synthesize...
14.
Aldholmi M, Ahmad R, Carretero-Molina D, Perez-Victoria I, Martin J, Reyes F, et al.
Angew Chem Int Ed Engl
. 2022 Mar;
61(23):e202203175.
PMID: 35325497
By limiting the nitrogen source to glutamic acid, we isolated cyclic peptides from Euglena gracilis containing asparagine and non-proteinogenic amino acids. Structure elucidation was accomplished through spectroscopic methods, mass spectrometry...
15.
Nadeem-Ul-Haque M, Bashir A, Karim H, Khan S, Shah Z, Jabeen A, et al.
J Pept Sci
. 2022 Jan;
28(8):e3405.
PMID: 35068012
The synthesis of the orbitide[1-8-NαC]-zanriorb A1, isolated from the medicinal plant Zanthoxylum riedelianum, was investigated by solution-phase macrocyclization of a linear peptide and on-resin solid-phase macrocyclization with an acylsulfonamide safety-catch...
16.
Vaidergorn M, da Silva Emery F, Ganesan A
J Med Chem
. 2021 Sep;
64(19):13980-14010.
PMID: 34591474
We review progress in the application of fragment-based drug discovery (FBDD) to epigenetic drug discovery (EPIDD) targeted at epigenetic writer and eraser enzymes as well as reader domains over the...
17.
Jansen N, Daniels C, Sunil T, Xu X, Cota J, Ganesan A, et al.
HIV Med
. 2021 Apr;
22(7):617-622.
PMID: 33899322
Objectives: HIV infection is associated with increased risk of erectile dysfunction (ED); however, factors associated with ED remain unclear. We evaluated the prevalence of ED among men living with HIV...
18.
Borrello M, Benelkebir H, Lee A, Tam C, Shafat M, Rushworth S, et al.
ChemMedChem
. 2021 Feb;
16(8):1316-1324.
PMID: 33533576
Lysine-specific demethylase 1 (LSD1/KDM1A) oxidatively removes methyl groups from histone proteins, and its aberrant activity has been correlated with cancers including acute myeloid leukemia (AML). We report a novel series...
19.
Piyasirananda W, Beekman A, Ganesan A, Bidula S, Stokes L
Mol Pharmacol
. 2020 Dec;
99(2):163-174.
PMID: 33334897
P2X7 is an important ligand-gated ion channel expressed in multiple immune cell populations. This study aimed to investigate the chemical requirements of triterpenoid glycosides within a new binding pocket to...
20.
Kawamura A, Ganesan A
Curr Opin Chem Biol
. 2020 Aug;
57:A1-A4.
PMID: 32800628
No abstract available.