A F Worrall
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Explore the profile of A F Worrall including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
106
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Recent Articles
1.
Jones S, Worrall A, Connolly B
J Mol Biol
. 1996 Dec;
264(5):1154-63.
PMID: 9000637
Bovine pancreatic deoxyribonuclease I (DNase I) is a well characterised endonuclease which cleaves double-stranded DNA to yield 5' phosphorylated polynucleotides. Co-crystal structures of DNase I with two different oligonucleotides have...
2.
Othman R, Baker S, Li Y, Worrall A, Wilton D
Biochim Biophys Acta
. 1996 Sep;
1303(2):92-102.
PMID: 8856038
A gene coding for human non-pancreatic (group II) secreted phospholipase A2 (hnpsPLA2) has been constructed by the single-step ligation of twelve synthetic oligonucleotides. The gene has been cloned into a...
3.
Doherty A, Worrall A, Connolly B
J Mol Biol
. 1995 Aug;
251(3):366-77.
PMID: 7650737
Bovine pancreatic deoxyribonuclease I is an endonuclease of low specificity that interacts with the minor groove of DNA. Two amino acids, R41 and Y76, completely fill this groove, with R41...
4.
Thumser A, Evans C, Worrall A, Wilton D
Biochem J
. 1994 Jan;
297 ( Pt 1):103-7.
PMID: 8280088
Rat liver fatty acid-binding protein is able to accommodate a wide range of non-polar anions in addition to long-chain fatty acids. The two arginine residues of rat liver fatty acid-binding...
5.
6.
Doherty A, Connolly B, Worrall A
Gene
. 1993 Dec;
136(1-2):337-40.
PMID: 8294027
A synthetic gene coding for bovine pancreatic DNaseI has been cloned under the control of a T7 promoter present on the plasmid pET11. This construct yields a stable Escherichia coli...
7.
Walker K, Worrall A, Gore M
Biochem Soc Trans
. 1992 Aug;
20(3):258S.
PMID: 1426550
No abstract available.
8.
Doherty A, Worrall A, Connolly B
Nucleic Acids Res
. 1991 Nov;
19(22):6129-32.
PMID: 1956772
The sequence selectivity of DNase 1 cleavage has been investigated by site-directed mutagenesis of a chemically synthesised gene. Two key DNA binding residues have been conservatively altered (Y76F and R41K)...
9.
Worrall A, Evans C, Wilton D
Biochem J
. 1991 Sep;
278 ( Pt 2):365-8.
PMID: 1898328
A gene coding for rat liver fatty-acid-binding protein (FABP) has been constructed by the single-step ligation of ten synthetic oligonucleotides. The gene has been cloned into the bacterial expression vector...
10.
Worrall A, Connolly B
J Biol Chem
. 1990 Dec;
265(35):21889-95.
PMID: 2254338
A gene coding for bovine pancreatic DNase I has been constructed from synthetic oligonucleotides. This gene has been cloned into a plasmid vector pDOC55 designed to allow very tight control...