A David Woolfson
Overview
Explore the profile of A David Woolfson including associated specialties, affiliations and a list of published articles.
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Articles
85
Citations
2059
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Recent Articles
1.
Larraneta E, Lutton R, Brady A, Vicente-Perez E, Woolfson A, Thakur R, et al.
Macromol Mater Eng
. 2016 Jun;
300(6):586-595.
PMID: 27346983
1A microwave (MW)-assisted crosslinking process to prepare hydrogel-forming microneedle (MN) arrays was evaluated. Conventionally, such MN arrays are prepared using processes that includes a thermal crosslinking step. Polymeric MN arrays...
2.
Larraneta E, Stewart S, Fallows S, Birkhauer L, McCrudden M, Woolfson A, et al.
Int J Pharm
. 2015 Dec;
497(1-2):62-9.
PMID: 26621687
The use of biological tissues in the in vitro assessments of dissolving (?) microneedle (MN) array mechanical strength and subsequent drug release profiles presents some fundamental difficulties, in part due...
3.
Lutton R, Larraneta E, Kearney M, Boyd P, Woolfson A, Donnelly R
Int J Pharm
. 2015 Aug;
494(1):417-29.
PMID: 26302858
A novel manufacturing process for fabricating microneedle arrays (MN) has been designed and evaluated. The prototype is able to successfully produce 14×14 MN arrays and is easily capable of scale-up,...
4.
Lutton R, Moore J, Larraneta E, Ligett S, Woolfson A, Donnelly R
Drug Deliv Transl Res
. 2015 May;
5(4):313-31.
PMID: 26022578
With interest in microneedles as a novel drug transdermal delivery system increasing rapidly since the late 1990s (Margetts and Sawyer Contin Educ Anaesthesia Crit Care Pain. 7(5):171-76, 2007), a diverse...
5.
Caffarel-Salvador E, Tuan-Mahmood T, McElnay J, McCarthy H, Mooney K, Woolfson A, et al.
Int J Pharm
. 2015 May;
489(1-2):158-69.
PMID: 25940042
Development of formulations and drug delivery strategies for paediatric use is challenging, partially due to the age ranges within this population, resulting in varying requirements to achieve optimised patient outcomes....
6.
McCrudden M, Zaid Alkilani A, Courtenay A, McCrudden C, McCloskey B, Walker C, et al.
Drug Deliv Transl Res
. 2015 Mar;
5(1):3-14.
PMID: 25787335
We describe, for the first time, considerations in the sterile manufacture of polymeric microneedle arrays. Microneedles (MN) made from dissolving polymeric matrices and loaded with the model drugs ovalbumin (OVA)...
7.
Donnelly R, McCrudden M, Zaid Alkilani A, Larraneta E, McAlister E, Courtenay A, et al.
PLoS One
. 2014 Nov;
9(10):e111547.
PMID: 25360806
We describe, for the first time, hydrogel-forming microneedle arrays prepared from "super swelling" polymeric compositions. We produced a microneedle formulation with enhanced swelling capabilities from aqueous blends containing 20% w/w...
8.
Donnelly R, Woolfson A
Ther Deliv
. 2014 Aug;
5(6):653-62.
PMID: 25090279
Research based upon microneedle (MN) arrays has intensified recently. While the initial focus was on biomolecules, the field has expanded to include delivery of conventional small-molecule drugs whose water solubility...
9.
Donnelly R, Juzenas P, McCarron P, Ma L, Woolfson A, Moan J
Photodiagnosis Photodyn Ther
. 2014 Jul;
3(3):190-201.
PMID: 25049154
Photodynamic therapy (PDT) is a medical treatment by which a combination of a photosensitising drug and visible light cause the destruction of selected cells. Thick lesions, such as nodular basal...
10.
Larraneta E, Moore J, Vicente-Perez E, Gonzalez-Vazquez P, Lutton R, Woolfson A, et al.
Int J Pharm
. 2014 Jun;
472(1-2):65-73.
PMID: 24877757
A commercial polymeric film (Parafilm M(®), a blend of a hydrocarbon wax and a polyolefin) was evaluated as a model membrane for microneedle (MN) insertion studies. Polymeric MN arrays were...