A Carolin Seefeldt
Overview
Explore the profile of A Carolin Seefeldt including associated specialties, affiliations and a list of published articles.
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8
Citations
276
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Recent Articles
1.
Direct Measurements of Erythromycin's Effect on Protein Synthesis Kinetics in Living Bacterial Cells
Seefeldt A, Aguirre Rivera J, Johansson M
J Mol Biol
. 2021 Mar;
433(10):166942.
PMID: 33744313
Macrolide antibiotics, such as erythromycin, bind to the nascent peptide exit tunnel (NPET) of the bacterial ribosome and modulate protein synthesis depending on the nascent peptide sequence. Whereas in vitro...
2.
Aguirre Rivera J, Larsson J, Volkov I, Seefeldt A, Sanyal S, Johansson M
Proc Natl Acad Sci U S A
. 2021 Feb;
118(9).
PMID: 33619089
The spread of antibiotic resistance is turning many of the currently used antibiotics less effective against common infections. To address this public health challenge, it is critical to enhance our...
3.
Herrero Del Valle A, Seip B, Cervera-Marzal I, Sacheau G, Seefeldt A, Innis C
Nat Microbiol
. 2020 Mar;
5(4):653-654.
PMID: 32218511
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
4.
Herrero Del Valle A, Seip B, Cervera-Marzal I, Sacheau G, Seefeldt A, Innis C
Nat Microbiol
. 2020 Feb;
5(4):554-561.
PMID: 32094585
Polyamines are essential metabolites that play an important role in cell growth, stress adaptation and microbial virulence. To survive and multiply within a human host, pathogenic bacteria adjust the expression...
5.
Volkov I, Seefeldt A, Johansson M
Methods
. 2019 Feb;
162-163:23-30.
PMID: 30742999
Chloramphenicol is a broad-spectrum antibiotic targeting the protein synthesis machinery by binding to the bacterial ribosome. Chloramphenicol has been considered a classic general inhibitor of translation, blocking the accommodation of...
6.
Graf M, Mardirossian M, Nguyen F, Seefeldt A, Guichard G, Scocchi M, et al.
Nat Prod Rep
. 2017 May;
34(7):702-711.
PMID: 28537612
Covering: up to 2017The innate immune system employs a broad array of antimicrobial peptides (AMPs) to attack invading microorganisms. While most AMPs act by permeabilizing the bacterial membrane, specific subclasses...
7.
Seefeldt A, Graf M, Perebaskine N, Nguyen F, Arenz S, Mardirossian M, et al.
Nucleic Acids Res
. 2016 Jan;
44(5):2429-38.
PMID: 26792896
Proline-rich antimicrobial peptides (PrAMPs) produced as part of the innate immune response of animals, insects and plants represent a vast, untapped resource for the treatment of multidrug-resistant bacterial infections. PrAMPs...
8.
Seefeldt A, Nguyen F, Antunes S, Perebaskine N, Graf M, Arenz S, et al.
Nat Struct Mol Biol
. 2015 May;
22(6):470-5.
PMID: 25984971
The increasing prevalence of multidrug-resistant pathogenic bacteria is making current antibiotics obsolete. Proline-rich antimicrobial peptides (PrAMPs) display potent activity against Gram-negative bacteria and thus represent an avenue for antibiotic development....