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A C S Hokken-Koelega

Explore the profile of A C S Hokken-Koelega including associated specialties, affiliations and a list of published articles. Areas
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Articles 64
Citations 980
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Recent Articles
1.
Damen L, Donze S, Grootjen L, Hokken-Koelega A
Psychoneuroendocrinology . 2021 Jul; 132:105335. PMID: 34225184
Context: Prader-Willi syndrome (PWS) is characterized by hypothalamic dysfunction. In children with PWS, stress-induced central adrenal insufficiency (CAI) has been described, however, daily life cortisol production may be normal. Hair...
2.
Vlaardingerbroek H, van den Akker E, Hokken-Koelega A
Endocr Connect . 2021 Apr; 10(5):R175-R188. PMID: 33884958
Obesity is reaching an epidemic state and has a major impact on health and economy. In most cases, obesity is caused by lifestyle factors. However, the risk of becoming obese...
3.
Donze S, Damen L, Mahabier E, Hokken-Koelega A
Eur J Endocrinol . 2020 Jan; 182(4):405-411. PMID: 31961800
Objective: Children with Prader-Willi syndrome (PWS) have mild to moderate cognitive impairment. Short-term studies showed positive effects of growth hormone (GH) on cognitive development. This study investigated the effects of...
4.
Goedegebuure W, Smeets C, Renes J, de Rijke Y, Hokken-Koelega A
Hum Reprod . 2018 Sep; 33(11):2122-2130. PMID: 30252068
Study Question: Is gonadal function affected in males and females with Silver-Russell Syndrome (SRS)? Summary Answer: Sertoli cell dysfunction is more common in males with SRS, with 11p15 LOM, but...
5.
Roelants J, Vermeulen M, Koning I, Groenenberg I, Willemsen S, Hokken-Koelega A, et al.
Pediatr Obes . 2017 Jul; 12 Suppl 1:65-71. PMID: 28752648
Background: The predisposition for obesity is suggested to originate in the prenatal period. Prenatal markers are needed to identify foetuses at risk for neonatal adiposity, as early marker of childhood...
6.
Kuppens R, Mahabier E, Bakker N, Siemensma E, Donze S, Hokken-Koelega A
Orphanet J Rare Dis . 2016 Nov; 11(1):153. PMID: 27852283
Background: Patients with Prader-Willi syndrome (PWS) have a cognitive impairment. Growth hormone (GH) treatment during childhood improves cognitive functioning, while cognition deteriorates in GH-untreated children with PWS. Cessation of GH...
7.
Kuppens R, Bakker N, Siemensma E, Donze S, Stijnen T, Hokken-Koelega A
Clin Endocrinol (Oxf) . 2016 Oct; 86(2):297-304. PMID: 27689944
Context: Patients with Prader-Willi syndrome (PWS) have an increased fat mass and decreased lean body mass. GH-treated young adults with PWS who have attained adult height benefit from continuation of...
8.
Kuppens R, Donze S, Hokken-Koelega A
Clin Endocrinol (Oxf) . 2016 Aug; 85(6):979-987. PMID: 27486141
Background: Prader-Willi syndrome (PWS) is known for hyperphagia with impaired satiety and a specific behavioural phenotype with stubbornness, temper tantrums, manipulative and controlling behaviour and obsessive-compulsive features. PWS is associated...
9.
Kuppens R, Delhanty P, Huisman T, Lely A, Hokken-Koelega A
Clin Endocrinol (Oxf) . 2016 May; 85(2):323-4. PMID: 27144882
No abstract available.
10.
Smeets C, Zandwijken G, Renes J, Hokken-Koelega A
J Clin Endocrinol Metab . 2016 Mar; 101(5):2105-12. PMID: 27007691
Context: Silver-Russell syndrome (SRS) is a genetically heterogeneous syndrome characterized by low birth weight, severe short stature, and variable dysmorphic features. GH treatment is a registered growth-promoting therapy for short...