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N E Bakker

Explore the profile of N E Bakker including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 173
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Recent Articles
1.
Kuppens R, Mahabier E, Bakker N, Siemensma E, Donze S, Hokken-Koelega A
Orphanet J Rare Dis . 2016 Nov; 11(1):153. PMID: 27852283
Background: Patients with Prader-Willi syndrome (PWS) have a cognitive impairment. Growth hormone (GH) treatment during childhood improves cognitive functioning, while cognition deteriorates in GH-untreated children with PWS. Cessation of GH...
2.
Kuppens R, Bakker N, Siemensma E, Donze S, Stijnen T, Hokken-Koelega A
Clin Endocrinol (Oxf) . 2016 Oct; 86(2):297-304. PMID: 27689944
Context: Patients with Prader-Willi syndrome (PWS) have an increased fat mass and decreased lean body mass. GH-treated young adults with PWS who have attained adult height benefit from continuation of...
3.
Bakker N, van Doorn J, Renes J, Donker G, Hokken-Koelega A
J Clin Endocrinol Metab . 2015 Jun; 100(8):3041-9. PMID: 26050733
Context: Children with Prader-Willi syndrome (PWS) attain high-serum immunoreactive IGF-1 levels during a standard-dose GH treatment, which leads to concern, but lowering the dose deteriorates their body composition. Objective: The...
4.
Kuppens R, Diene G, Bakker N, Molinas C, Faye S, Nicolino M, et al.
Endocrine . 2015 May; 50(3):633-42. PMID: 25989955
Prader-Willi syndrome (PWS) is characterized by a switch from failure to thrive to excessive weight gain and hyperphagia in early childhood. Hyperghrelinemia may be involved in the underlying mechanisms of...
5.
Bakker N, Siemensma E, Koopman C, Hokken-Koelega A
Horm Res Paediatr . 2015 Mar; 83(5):321-31. PMID: 25764996
Background/aims: Dietary management is a difficult but key aspect of care in children with Prader-Willi syndrome (PWS). We therefore investigated the effect of growth hormone (GH) treatment on reported energy...
6.
Bakker N, Kuppens R, Siemensma E, Tummers-de Lind van Wijngaarden R, Festen D, Bindels-de Heus G, et al.
J Clin Endocrinol Metab . 2015 Feb; 100(4):1609-18. PMID: 25668198
Context: Longitudinal data on bone mineral density (BMD) in children and adolescents with Prader-Willi Syndrome (PWS) during long-term GH treatment are not available. Objective: This study aimed to determine effects...
7.
Bakker N, Wolffenbuttel K, Looijenga L, Hokken-Koelega A
J Urol . 2014 Aug; 193(1):291-8. PMID: 25109686
Purpose: Boys with Prader-Willi syndrome often have undescended testes. Prospective studies on the treatment of cryptorchidism in these patients are lacking. We evaluated the effects of human chorionic gonadotropin administration...
8.
Bakker N, Kuppens R, Siemensma E, Tummers-de Lind van Wijngaarden R, Festen D, Bindels-de Heus G, et al.
J Clin Endocrinol Metab . 2013 Sep; 98(10):4013-22. PMID: 24001750
Background: The most important reason for treating children with Prader-Willi syndrome (PWS) with GH is to optimize their body composition. Objectives: The aim of this ongoing study was to determine...