A C S Hokken-Koelega
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Explore the profile of A C S Hokken-Koelega including associated specialties, affiliations and a list of published articles.
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64
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Recent Articles
11.
Kuppens R, Delhanty P, Huisman T, Lely A, Hokken-Koelega A
Clin Endocrinol (Oxf)
. 2016 Feb;
85(3):488-94.
PMID: 26850227
Background: Prader-Willi syndrome (PWS) is characterized by hyperphagia with impaired satiety. PWS patients have very high acylated ghrelin (AG) with normal unacylated ghrelin (UAG) levels, resulting in an elevated AG/UAG...
12.
Bakker N, van Doorn J, Renes J, Donker G, Hokken-Koelega A
J Clin Endocrinol Metab
. 2015 Jun;
100(8):3041-9.
PMID: 26050733
Context: Children with Prader-Willi syndrome (PWS) attain high-serum immunoreactive IGF-1 levels during a standard-dose GH treatment, which leads to concern, but lowering the dose deteriorates their body composition. Objective: The...
13.
Kuppens R, Diene G, Bakker N, Molinas C, Faye S, Nicolino M, et al.
Endocrine
. 2015 May;
50(3):633-42.
PMID: 25989955
Prader-Willi syndrome (PWS) is characterized by a switch from failure to thrive to excessive weight gain and hyperphagia in early childhood. Hyperghrelinemia may be involved in the underlying mechanisms of...
14.
Lo S, Collin P, Hokken-Koelega A
J Intellect Disabil Res
. 2015 Apr;
59(9):827-34.
PMID: 25871504
Background: Prader-Willi syndrome (PWS) is characterised by hypotonia, hypogonadism, short stature, obesity, behavioural problems, intellectual disability, and delay in language, social and motor development. There is very limited knowledge about...
15.
Bakker N, Siemensma E, Koopman C, Hokken-Koelega A
Horm Res Paediatr
. 2015 Mar;
83(5):321-31.
PMID: 25764996
Background/aims: Dietary management is a difficult but key aspect of care in children with Prader-Willi syndrome (PWS). We therefore investigated the effect of growth hormone (GH) treatment on reported energy...
16.
Lo S, Collin P, Hokken-Koelega A
Am J Med Genet A
. 2015 Feb;
167A(5):983-91.
PMID: 25712902
Psychiatric disorders such as psychosis are highly prevalent in adults with Prader-Willi syndrome (PWS). However, knowledge about the presence and progression of psychiatric disorders in children with PWS is very...
17.
Bakker N, Kuppens R, Siemensma E, Tummers-de Lind van Wijngaarden R, Festen D, Bindels-de Heus G, et al.
J Clin Endocrinol Metab
. 2015 Feb;
100(4):1609-18.
PMID: 25668198
Context: Longitudinal data on bone mineral density (BMD) in children and adolescents with Prader-Willi Syndrome (PWS) during long-term GH treatment are not available. Objective: This study aimed to determine effects...
18.
Renes J, Willemsen R, Mulder J, Bakker-van Waarde W, Rotteveel J, Oostdijk W, et al.
Clin Endocrinol (Oxf)
. 2014 Nov;
82(6):854-61.
PMID: 25409576
Background: Growth hormone (GH) treatment is effective in improving adult height (AH) in short children born SGA. However, there is a wide variation in height gain, even after adjustment for...
19.
Bakker N, Wolffenbuttel K, Looijenga L, Hokken-Koelega A
J Urol
. 2014 Aug;
193(1):291-8.
PMID: 25109686
Purpose: Boys with Prader-Willi syndrome often have undescended testes. Prospective studies on the treatment of cryptorchidism in these patients are lacking. We evaluated the effects of human chorionic gonadotropin administration...
20.
Renes J, van Doorn J, Hokken-Koelega A
J Clin Endocrinol Metab
. 2014 Jun;
99(10):E1988-96.
PMID: 24926947
Background: IGF-I is mainly sequestered in a 150-kDa ternary complex with IGF binding protein (IGFBP)-3 and the acid-labile subunit. Data on complex formation and factors influencing formation have not been...