A Bracher
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Explore the profile of A Bracher including associated specialties, affiliations and a list of published articles.
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19
Citations
391
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Recent Articles
1.
Wang H, Yan X, Aigner H, Bracher A, Nguyen N, Hee W, et al.
Nature
. 2019 Jan;
566(7742):131-135.
PMID: 30675061
Cells use compartmentalization of enzymes as a strategy to regulate metabolic pathways and increase their efficiency. The α- and β-carboxysomes of cyanobacteria contain ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco)-a complex of eight large...
2.
Aigner H, Wilson R, Bracher A, Calisse L, Bhat J, Hartl F, et al.
Science
. 2017 Dec;
358(6368):1272-1278.
PMID: 29217567
Plant RuBisCo, a complex of eight large and eight small subunits, catalyzes the fixation of CO in photosynthesis. The low catalytic efficiency of RuBisCo provides strong motivation to reengineer the...
3.
Hoppe C, Klaas C, Ossebaar S, Soppa M, Cheah W, Laglera L, et al.
Deep Sea Res 2 Top Stud Oceanogr
. 2017 May;
138:63-73.
PMID: 28515575
The Antarctic Circumpolar Current has a high potential for primary production and carbon sequestration through the biological pump. In the current study, two large-scale blooms observed in 2012 during a...
4.
Stamm A, Weiler M, Bracher A, Schwing K, Gerhards M
Phys Chem Chem Phys
. 2014 Sep;
16(39):21795-803.
PMID: 25200683
In this paper the excited state proton transfer (ESPT) of isolated 3-hydroxychromone (3-HC), the prototype of the flavonols, is investigated for the first time by combined IR/UV spectroscopy in molecular...
5.
Bracher A, Hoch S, Albert K, Kost H, Werner B, von Harbou E, et al.
J Magn Reson
. 2014 Mar;
242:155-61.
PMID: 24650728
A novel nuclear magnetic resonance (NMR) probe head for monitoring fast chemical reactions is described. It combines micro-reaction technology with capillary flow NMR spectroscopy. Two reactants are fed separately into...
6.
Schramek N, Bracher A, Bacher A
J Biol Chem
. 2001 Sep;
276(47):44157-62.
PMID: 11553632
GTP cyclohydrolase II catalyzes the conversion of GTP into a mixture of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (Compound 2), formate, and pyrophosphate. Moreover, GMP was recently shown to be formed as a minor...
7.
Bracher A, Schramek N, Bacher A
Biochemistry
. 2001 Jun;
40(26):7896-902.
PMID: 11425318
GTP cyclohydrolase I catalyzes a mechanistically complex ring expansion affording dihydroneopterin triphosphate from GTP. The inherently slow enzyme reaction was studied under single turnover conditions monitored by multiwavelength ultraviolet spectroscopy....
8.
Ritz H, Schramek N, Bracher A, Herz S, Eisenreich W, Richter G, et al.
J Biol Chem
. 2001 Apr;
276(25):22273-7.
PMID: 11301327
GTP cyclohydrolase II catalyzes the first committed reaction in the biosynthesis of the vitamin riboflavin. The recombinant enzyme from Escherichia coli is shown to produce 2,5-diamino-6-beta-ribosylamino-4(3H)-pyrimidinone 5'-phosphate and GMP at...
9.
Bracher A, Weissenhorn W
J Mol Biol
. 2001 Feb;
306(1):7-13.
PMID: 11178889
Sec1 molecules associate with t-SNAREs from the syntaxin family in a heterodimeric complex that plays an essential role in vesicle transport and membrane fusion. Neuronal rat n-Sec1 has an arch-shaped...
10.
Auerbach G, Herrmann A, Bracher A, Bader G, Gutlich M, Fischer M, et al.
Proc Natl Acad Sci U S A
. 2000 Nov;
97(25):13567-72.
PMID: 11087827
The crystal structure of recombinant human GTP cyclohydrolase I was solved by Patterson search methods by using the coordinates of the Escherichia coli enzyme as a model. The human as...