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A A Spector

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Articles 258
Citations 3681
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Recent Articles
1.
Spector A, Deo N, Grosh K, Ratnanather J, Raphael R
J Membr Biol . 2006 Jun; 209(2-3):135-52. PMID: 16773498
The outer hair cell (OHC) is an extremely specialized cell and its proper functioning is essential for normal mammalian hearing. This article reviews recent developments in theoretical modeling that have...
2.
Spector A, Ameen M, Schmiedt R
Biomech Model Mechanobiol . 2003 Nov; 1(2):123-35. PMID: 14595545
We analyze the deformation of the outer hair cell and its production of active force under physiological conditions. The active force has two components. One results from the strain caused...
3.
Williard D, Harmon S, Kaduce T, Spector A
Prostaglandins Leukot Essent Fatty Acids . 2002 Sep; 67(2-3):99-104. PMID: 12324227
Astrocytes convert n-6 fatty acids primarily to arachidonic acid (20:4n-6), whereas n-3 fatty acids are converted to docosapentaenoic (22:5n-3) and docosahexaenoic (22:6n-3) acids. The utilization of 20-, 22- and 24-carbon...
4.
Williard D, Harmon S, Preuss M, Kaduce T, Moore S, Spector A
World Rev Nutr Diet . 2002 Apr; 88:168-72. PMID: 11935950
No abstract available.
5.
Lu T, Hoshi T, Weintraub N, Spector A, Lee H
J Physiol . 2001 Dec; 537(Pt 3):811-27. PMID: 11744757
1. We examined the effects of epoxyeicosatrienoic acids (EETs), which are cytochrome P450 metabolites of arachidonic acid (AA), on the activities of the ATP-sensitive K(+) (K(ATP)) channels of rat cardiac...
6.
Ferdinandusse S, Denis S, Mooijer P, Zhang Z, Reddy J, Spector A, et al.
J Lipid Res . 2001 Dec; 42(12):1987-95. PMID: 11734571
DHA (C22:6n-3) is an important PUFA implicated in a number of (patho)physiological processes. For a long time, the exact mechanism of DHA formation has remained unclear, but now it is...
7.
Williard D, Harmon S, Kaduce T, Preuss M, Moore S, Robbins M, et al.
J Lipid Res . 2001 Aug; 42(9):1368-76. PMID: 11518755
DHA, the main n-3 PUFA in the brain, is synthesized from n-3 PUFA precursors by astrocytes. To assess the potential of this process to supply DHA for the brain, we...
8.
Lu T, Katakam P, VanRollins M, Weintraub N, Spector A, Lee H
J Physiol . 2001 Aug; 534(Pt 3):651-67. PMID: 11483698
1. Dihydroxyeicosatrienoic acids (DHETs), which are metabolites of arachidonic acid (AA) and epoxyeicosatrienoic acids (EETs), have been identified as highly potent endogenous vasodilators, but the mechanisms by which DHETs induce...
9.
Watkins P, Hamilton J, Leaf A, Spector A, Moore S, Anderson R, et al.
J Mol Neurosci . 2001 Aug; 16(2-3):87-92; discussion 151-7. PMID: 11478388
The brain is rich in diverse fatty acids saturated, monounsaturated and polyunsaturated fatty acids with chain lengths ranging from less than 16 to more than 24 carbons that make up...
10.
Katz R, Hamilton J, Spector A, Moore S, Moser H, Noetzel M, et al.
J Mol Neurosci . 2001 Aug; 16(2-3):333-5. PMID: 11478387
A primary goal of the international workshop "Brain Uptake and Utilization of Fatty Acids" was to identify research areas that would benefit from further investigation. The major themes for future...